Recent progress of bioactivities, mechanisms of action, total synthesis, structural modifications and structure-activity relationships of indole derivatives: a review
T Li, H Xu - Mini Reviews in Medicinal Chemistry, 2022 - ingentaconnect.com
… This mini-review has summarized the recent developments from 2018 to 2020 on mechanisms
of action, total synthesis, structural modifications, and structure-activity relationships of …
of action, total synthesis, structural modifications, and structure-activity relationships of …
Focus on modified microcins: structural features and mechanisms of action
D Destoumieux-Garzón, J Peduzzi, S Rebuffat - Biochimie, 2002 - Elsevier
… modified microcins that show very original structures. We present an updated overview on the
structures and mechanisms of action … , which include specific modification enzymes, export …
structures and mechanisms of action … , which include specific modification enzymes, export …
Biosynthesis, total synthesis, structural modifications, bioactivity, and mechanism of action of the quinonemethide triterpenoid celastrol
Y Lu, Y Liu, J Zhou, D Li, W Gao - Medicinal research reviews, 2021 - Wiley Online Library
… To search for druglike derivatives, several structurally modified compounds were … ,
total synthesis, structural modifications, bioactivity, and mechanism of action of celastrol. We …
total synthesis, structural modifications, bioactivity, and mechanism of action of celastrol. We …
Vancomycin C-terminus guanidine modifications and further insights into an added mechanism of action imparted by a peripheral structural modification
… of this newly introduced mechanism of action by the guanidine modification, we conducted …
of the two mechanisms of action attributable to the CBP and guanidine modifications requires …
of the two mechanisms of action attributable to the CBP and guanidine modifications requires …
What structural features determine repair enzyme specificity and mechanism in chemically modified DNA?
B Singer, B Hang - Chemical research in toxicology, 1997 - ACS Publications
… a base modification (eg, pBQ-dC) can cause a local structural … modified an AP site and
found that an urea residue or O-alkylhydroxylamines did not prevent 5‘-cleavage of the modified …
found that an urea residue or O-alkylhydroxylamines did not prevent 5‘-cleavage of the modified …
The structural modification of natural products for novel drug discovery
… of structural modifications of NPs in drug discovery, including deciphering the mode of
actions, overcoming multidrug resistance, repurposing of drugs, structural simplification, …
actions, overcoming multidrug resistance, repurposing of drugs, structural simplification, …
Tubulin posttranslational modifications: enzymes and their mechanisms of action
TH MacRae - European Journal of Biochemistry, 1997 - Wiley Online Library
… phase, but its action on microtubules within these structures is uncertain. As another example
of tyrosine kinase activity, a-tubulin and p-tubulin are modified during monocytic differentia…
of tyrosine kinase activity, a-tubulin and p-tubulin are modified during monocytic differentia…
Matrine: Bioactivities and structural modifications
J Huang, H Xu - Current Topics in Medicinal Chemistry, 2016 - ingentaconnect.com
… Especially the mechanism of action of anticancer … tural modifications of matrine and its
derivatives are summarized from 2010 to 2015. Additionally, the mechanism of action and structure…
derivatives are summarized from 2010 to 2015. Additionally, the mechanism of action and structure…
Alteration of nucleosome structure as a mechanism of transcriptional regulation
JL Workman, RE Kingston - Annual review of biochemistry, 1998 - annualreviews.org
… The direct modification of nucleosome structure bythese … areless structured and extend out
of the central structured … we relate these modifications tochanges in the structural properties of …
of the central structured … we relate these modifications tochanges in the structural properties of …
Anti-cancer peptides: classification, mechanism of action, reconstruction and modification
M Xie, D Liu, Y Yang - Open biology, 2020 - royalsocietypublishing.org
… side chain modification. After summarizing the classification and mechanism of action of ACPs,
… and progress about their reconstruction and modification. The information collected here …
… and progress about their reconstruction and modification. The information collected here …
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- structure activity relationships mechanisms of action
- structural modifications indole derivatives