… ious medicines, total synthesis, structural modifications, and mechanisms of action of indole
and its derivatives have received much attention in the fields of synthetic organic chemistry …

… The total synthesis of celastrol was realized for the first time … derivatives, several structurally
modified compounds were … biosynthesis, total synthesis, structural modifications, bioactivity, …

… Through clever structural modification of FK506 by semisynthesis, Schreiber and co-workers
were able to produce an affigel-based affinity matrix 67 for FK506 as well as a 14 C40-…

… was primarily for structure−activity … The synthesis of 2 can be simplified by utilizing
desepoxyarenastatin 4 as the final precursor with epoxidation being the last step in the total …

… molecular structure and extensive … synthesis and structural modification of lycorine are
summarized in this review. Keywords lycorine; total synthesis; derivatives; structure modification …

… Rather than targeting product structures that … structural modifications that require a
synthesis-driven editing of the molecular framework according to the logic of “diverted total synthesis”.…

… structure and highly promising antibiotic activity of the MPPs, we began our attempt at the
total synthesis of this … of l-βhEnd 39 was achieved that was based on modification of a method …

… research activities directed toward their chemical synthesis, structural modification, and
biological evaluation. As a result of this surge, total syntheses of several naturally occurring …

… Finally, a more profound structural modification was procured on treatment of 14 with
TBAF; by virtue of the basic character of this reagent, the incipient diol 15 engages in a …

… structural modifications to the vindoline core ring system. (35) These latter efforts represent
one of few examples of productive core structure … The identification of structural analogues …