BRAF Mutation in Papillary Thyroid Cancer: Pathogenic Role, Molecular Bases, and Clinical Implications

M Xing - Endocrine reviews, 2007 - academic.oup.com
… Thus, the T1799A mutation is virtually the only BRAF mutation identified in thyroid cancer (…
in familial thyroid cancer (49, 50). A striking finding on BRAF mutation in thyroid cancer is its …

Prognostic utility of BRAF mutation in papillary thyroid cancer

M Xing - Molecular and cellular endocrinology, 2010 - Elsevier
Papillary thyroid cancer (PTC) is a common endocrine malignancy that frequently harbors the
oncogenic T1799A BRAF mutation. As a … In PTC, BRAF mutation is closely associated with …

BRAF mutation in papillary thyroid cancer and its value in tailoring initial treatment: a systematic review and meta-analysis

RP Tufano, GV Teixeira, J Bishop, KA Carson, M Xing - Medicine, 2012 - journals.lww.com
… of thyroid cancer, papillary thyroid cancer (PTC)—a tumor type … the association of BRAF
mutation with PTC recurrence or … to investigate correlations of BRAF mutation status with PTC …

BRAF mutation in papillary thyroid carcinoma

Y Cohen, M Xing, E Mambo, Z Guo… - … the National Cancer …, 2003 - academic.oup.com
… analyzed nine common thyroid cell lines (… BRAF mutation in six (67%) of the nine lines. We
also completely sequenced exons 11 and 15 in all T1796A-negative papillary thyroid cancers

BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer

M Xing, WH Westra, RP Tufano, Y Cohen… - The Journal of …, 2005 - academic.oup.com
… shown that this BRAF mutation occurs in papillary thyroid cancer (PTC) … BRAF mutation
occurs exclusively in PTC and PTC-derived anaplastic thyroid cancers but not in normal thyroid

Clinical Implication of Hot Spot BRAF Mutation, V599E, in Papillary Thyroid Cancers

H Namba, M Nakashima, T Hayashi… - The Journal of …, 2003 - academic.oup.com
… human thyroid cancers. We detected BRAF mutation, V599E, in four of six human thyroid
cancer cell lines and in 51 of 207 thyroid tumor tissues. The correlation analysis using various …

The prevalence and prognostic value of BRAF mutation in thyroid cancer

E Kebebew, J Weng, J Bauer, G Ranvier… - Annals of …, 2007 - journals.lww.com
… of BRAF mutation among thyroid cancer histologic subtypes and determine the association
of BRAF mutation with indicators of poor prognosis for papillary thyroid cancer and patient …

BRAF mutation in papillary thyroid carcinoma: pathogenic role and clinical implications

KT Tang, CH Lee - Journal of the chinese medical association, 2010 - journals.lww.com
… the most rapidly increasing cancer among women and the … thyroid cancers are classified
into papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), and anaplastic thyroid cancer

Higher rate of BRAF mutation in papillary thyroid cancer over time A single‐institution study

A Mathur, W Moses, R Rahbari, E Khanafshar… - Cancer, 2011 - Wiley Online Library
… because of differences in disease aggressiveness, as the extent of disease across all 3 groups
… rate of BRAF mutation during a time in which the incidence of thyroid cancer has doubled …

[HTML][HTML] BRAF mutation in papillary thyroid carcinoma

X Li, AB Abdel-Mageed, E Kandil - International journal of clinical …, 2012 - ncbi.nlm.nih.gov
BRAF mutation is the most common genetic alternation in thyroid cancer, particularly in
papillary thyroid cancer (… /MAPK signaling pathway due to BRAF mutation plays a central role in …