BRAF Mutation in Papillary Thyroid Cancer: Pathogenic Role, Molecular Bases, and Clinical Implications
M Xing - Endocrine reviews, 2007 - academic.oup.com
… Thus, the T1799A mutation is virtually the only BRAF mutation identified in thyroid cancer (…
in familial thyroid cancer (49, 50). A striking finding on BRAF mutation in thyroid cancer is its …
in familial thyroid cancer (49, 50). A striking finding on BRAF mutation in thyroid cancer is its …
Prognostic utility of BRAF mutation in papillary thyroid cancer
M Xing - Molecular and cellular endocrinology, 2010 - Elsevier
… Papillary thyroid cancer (PTC) is a common endocrine malignancy that frequently harbors the
oncogenic T1799A BRAF mutation. As a … In PTC, BRAF mutation is closely associated with …
oncogenic T1799A BRAF mutation. As a … In PTC, BRAF mutation is closely associated with …
BRAF mutation in papillary thyroid cancer and its value in tailoring initial treatment: a systematic review and meta-analysis
… of thyroid cancer, papillary thyroid cancer (PTC)—a tumor type … the association of BRAF
mutation with PTC recurrence or … to investigate correlations of BRAF mutation status with PTC …
mutation with PTC recurrence or … to investigate correlations of BRAF mutation status with PTC …
BRAF mutation in papillary thyroid carcinoma
Y Cohen, M Xing, E Mambo, Z Guo… - … the National Cancer …, 2003 - academic.oup.com
… analyzed nine common thyroid cell lines (… BRAF mutation in six (67%) of the nine lines. We
also completely sequenced exons 11 and 15 in all T1796A-negative papillary thyroid cancers …
also completely sequenced exons 11 and 15 in all T1796A-negative papillary thyroid cancers …
BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer
M Xing, WH Westra, RP Tufano, Y Cohen… - The Journal of …, 2005 - academic.oup.com
… shown that this BRAF mutation occurs in papillary thyroid cancer (PTC) … BRAF mutation
occurs exclusively in PTC and PTC-derived anaplastic thyroid cancers but not in normal thyroid …
occurs exclusively in PTC and PTC-derived anaplastic thyroid cancers but not in normal thyroid …
Clinical Implication of Hot Spot BRAF Mutation, V599E, in Papillary Thyroid Cancers
H Namba, M Nakashima, T Hayashi… - The Journal of …, 2003 - academic.oup.com
… human thyroid cancers. We detected BRAF mutation, V599E, in four of six human thyroid
cancer cell lines and in 51 of 207 thyroid tumor tissues. The correlation analysis using various …
cancer cell lines and in 51 of 207 thyroid tumor tissues. The correlation analysis using various …
The prevalence and prognostic value of BRAF mutation in thyroid cancer
E Kebebew, J Weng, J Bauer, G Ranvier… - Annals of …, 2007 - journals.lww.com
… of BRAF mutation among thyroid cancer histologic subtypes and determine the association
of BRAF mutation with indicators of poor prognosis for papillary thyroid cancer and patient …
of BRAF mutation with indicators of poor prognosis for papillary thyroid cancer and patient …
Optimizing surgical treatment of papillary thyroid carcinoma associated with BRAF mutation
L Yip, MN Nikiforova, SE Carty, JH Yim, MT Stang… - Surgery, 2009 - Elsevier
… is the most common genetic alteration found in papillary thyroid carcinoma (PTC) and is
associated with extrathyroidal extension, lymph node metastasis, and tumor recurrence. It is not …
associated with extrathyroidal extension, lymph node metastasis, and tumor recurrence. It is not …
BRAF mutation in papillary thyroid carcinoma: pathogenic role and clinical implications
KT Tang, CH Lee - Journal of the chinese medical association, 2010 - journals.lww.com
… the most rapidly increasing cancer among women and the … thyroid cancers are classified
into papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), and anaplastic thyroid cancer …
into papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), and anaplastic thyroid cancer …
The BRAF mutation is useful for prediction of clinical recurrence in low‐risk patients with conventional papillary thyroid carcinoma
TY Kim, WB Kim, YS Rhee, JY Song… - Clinical …, 2006 - Wiley Online Library
Background The activating BRAF V600E mutation is the most common genetic alteration
reported in papillary thyroid carcinoma (PTC). While some reports suggest the BRAF V600E …
reported in papillary thyroid carcinoma (PTC). While some reports suggest the BRAF V600E …
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