Clinical Implication of Hot Spot BRAF Mutation, V599E, in Papillary Thyroid Cancers

H Namba, M Nakashima, T Hayashi… - The Journal of …, 2003 - academic.oup.com
… human thyroid cancers. We detected BRAF mutation, V599E, in four of six human thyroid
cancer cell lines and in 51 of 207 thyroid tumor tissues. The correlation analysis using various …

Clinical Significance of BRAF Mutation in Thyroid Papillary Cancer

IJ Fernandez, O Piccin, S Sciascia… - … –Head and Neck …, 2013 - journals.sagepub.com
BRAF mutation represents the most common oncogenic event in sporadic papillary thyroid
cancer (PTC). There are, however, significant discrepancies regarding the overall frequency …

BRAFV600E Mutation is Associated with Tumor Aggressiveness in Papillary Thyroid Cancer

S Kim, KE Lee, JP Myong, J Park, YK Jeon… - World journal of …, 2012 - Springer
… the most common genetic alteration found in papillary thyroid cancer (PTC). Recent studies
… Also, we found a somewhat higher rate of BRAF mutation in advanced stage PTC [138/191 (…

Mutations of the BRAF gene in papillary thyroid carcinoma and in Hashimoto's thyroiditis

KH Kim, KS Suh, DW Kang, DY Kang - Pathology international, 2005 - Wiley Online Library
papillary thyroid carcinoma (PTC) and Hashimoto's thyroiditis (HT) and to evaluate the
association of the BRAF mutation … The BRAF mutation V599E in papillary thyroid carcinoma (PTC) …

BRAF mutation in papillary thyroid cancer—Prevalence and clinical correlation in a South‐East Asian cohort

X Goh, J Lum, SP Yang, SB Chionh… - Clinical …, 2019 - Wiley Online Library
… of the BRAF mutation in our cohort of papillary thyroid cancer patients was 56%. BRAF
mutation-positive tumours were associated with a more locally advanced disease, and these …

[PDF][PDF] BRAF (V600E) mutation and the biology of papillary thyroid cancer

F Frasca, C Nucera, G Pellegriti, P Gangemi… - … -related cancer, 2008 - academia.edu
… Oler G, Ebina KN, Michaluart P Jr, Kimura ET & Cerutti J 2005 Investigation of BRAF mutation
in a series of papillary thyroid carcinoma and matched-lymph node metastasis reveals a …

Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer

M Xing, AS Alzahrani, KA Carson, D Viola, R Elisei… - Jama, 2013 - jamanetwork.com
… BRAF V600E is a prominent oncogene in papillary thyroid cancer (PTC), but its role in PTC-…
Because overall mortality in PTC is low and the association was not independent of tumor

BRAF mutations in papillary carcinomas of the thyroid

T Fukushima, S Suzuki, M Mashiko, T Ohtake, Y Endo… - Oncogene, 2003 - nature.com
… cases of thyroid carcinoma to investigate … BRAF mutation is sufficient to activate the
RAS-mediated mitogenic signaling, and thus RAS mutation is not observed in papillary carcinoma

BRAF mutation is not predictive of long‐term outcome in papillary thyroid carcinoma

LE Henke, JD Pfeifer, C Ma, SM Perkins… - Cancer …, 2015 - Wiley Online Library
… , and classic papillary histology remained independently predictive of the BRAF mutation on
… The significant association between the BRAF mutation and the classic papillary histologic …

BRAF mutations are associated with some histological types of papillary thyroid carcinoma

V Trovisco, I Vieira de Castro, P Soares… - The Journal of …, 2004 - Wiley Online Library
… high prevalence in melanoma and papillary thyroid carcinoma (PTC). … thyroid lesions. In
order to unravel whether there is any association between the occurrence of the BRAF mutation