Phase III trial comparing a defined duration of therapy versus continuous therapy followed by second-line therapy in advanced-stage IIIB/IV non–small-cell lung cancer

MA Socinski, MJ Schell, A Peterman, K Bakri… - Journal of Clinical …, 2002 - ascopubs.org
… PURPOSE: To compare four cycles of therapy versus continuous therapy to determine
the optimal duration of chemotherapy in advanced non–small-cell lung cancer (NSCLC). …

Maintenance therapy with continuous or switch strategy in advanced non-small cell lung cancer: a systematic review and meta-analysis

X Zhang, J Zang, J Xu, C Bai, Y Qin, K Liu, C Wu, M Wu… - Chest, 2011 - Elsevier
… therapy for patients with advanced non-small cell lung cancer. Non-small cell lung cancer
(NSCLC) is the leading cause of cancer mortality in industrialized countries. The current …

Continuous versus Alternating Combination Chemotherapy for Advanced Small Cell Carcinoma of the Lung

K Østerlind, S Sörenson, HH Hansen… - Cancer research, 1983 - AACR
… , 146 patients with small cell carcinoma of the lung, staged as … among patients receiving
continuous therapy compared to … with advanced small cell lung cancer. Continuous regimen ( …

Continuous versus 1-year fixed-duration nivolumab in previously treated advanced non–small-cell lung cancer: CheckMate 153

DM Waterhouse, EB Garon, J Chandler… - Journal of Clinical …, 2020 - ascopubs.org
… of immunotherapy, including for non–small-cell lung cancer (NSCLC). We present an …
of 1-year fixed-duration versus continuous therapy on the efficacy and safety of nivolumab. …

… of standard chemotherapy versus alternating chemotherapy and maintenance versus no maintenance therapy for extensive-stage small-cell lung cancer: a phase III …

DS Ettinger, DM Finkelstein, MD Abeloff… - Journal of Clinical …, 1990 - ascopubs.org
… the continuous therapy, the magnitude of the increase is small, 3 months or less. Havermann
et al also reported an increase in 2-year survival from 3% to 6% in patients receiving the …

Strategies for prolonged therapy in patients with advanced non–small-cell lung cancer

P Fidias, S Novello - Journal of Clinical Oncology, 2010 - ascopubs.org
… A key challenge in the treatment of advanced non–small-cell lung cancer (NSCLC) is
improving outcomes for patients who have achieved at least stable disease after standard first-line …

Cyclic-alternating versus response-oriented chemotherapy in small-cell lung cancer: a German multicenter randomized trial of 321 patients.

M Wolf, M Pritsch, P Drings, K Hans… - Journal of clinical …, 1991 - ascopubs.org
… and not cross-resistant, (3) the application of additional treatment strategies such as
radiotherapy or surgery, and (4) the criteria and time for shifting patients from continuous therapy to …

Alternating chemotherapy in small cell lung cancer

M Wolf, K Havemann - Oncology Research and Treatment, 1990 - karger.com
… treatment modality in small cell lung cancer. This approach has … a period of initial common
continuous therapy. The results of … performed continuous therapy in small cell lung cancer. …

[HTML][HTML] Maintenance therapies for non-small cell lung cancer

N Blais, E Kassouf - Frontiers in Oncology, 2014 - frontiersin.org
Treatment of lung cancer had evolved during the last decade with the introduction of new
chemotherapeutic regimens and targeted therapies. However, the maximum benefit reached …

[HTML][HTML] Maintenance therapy in advanced non-small cell lung cancer: current status and future implications

TE Stinchcombe, MA Socinski - Journal of Thoracic Oncology, 2011 - Elsevier
Lung cancer is the leading cause of cancer mortality in the United States, and it is estimated
… million deaths related to lung cancer worldwide.1, 2 Non-small cell lung cancer (NSCLC) …