Evaluation of common genes and molecular pathways between atherosclerosis and inflammatory bowel disease: A systems biology approach

S Shafieipour, M Mohammadtaghizadeh - Human Gene, 2024 - Elsevier
Systems biology approaches are a novel method used today to identify shared genes and
molecular pathways between diseases. Furthermore, this approach is used to identify genes …

Systems biology in inflammatory bowel diseases: ready for prime time

C Polytarchou, G Koukos… - Current opinion in …, 2014 - journals.lww.com
colitis and Crohn's disease are the two predominant types of inflammatory bowel disease
(… The purpose of this review is to describe a systems biology approach to IBD as a novel and …

Improving prediction of disease outcome for inflammatory bowel disease: progress through systems medicine

F Giachero, A Jenke, M Zilbauer - Expert Review of Clinical …, 2021 - Taylor & Francis
… to implement systems biology approaches in medical concepts, research and practice. Its
principle is to analyze diseases in a holistic manner, by integrating systems biology platforms …

Cell‐level systems biology model to study inflammatory bowel diseases and their treatment options

S Stübler, C Kloft, W Huisinga - CPT: Pharmacometrics & …, 2023 - Wiley Online Library
… To help understand the complex and therapeutically challenging inflammatory bowel
diseases (IBDs), we developed a systems biology model of the intestinal immune system that is …

[HTML][HTML] A systems biology analysis protein-protein interaction of NASH and IBD based on comprehensive gene information

R Karbalaei, M Piran, M Rezaei-Tavirani… - … and hepatology from …, 2017 - ncbi.nlm.nih.gov
… molecular mechanisms in related diseases such as IBD and … in systems biology in which
analyzed complex interactome of proteins as a main source of data (26). Using systems biology

P039 Identifying Key Genes in CROHN'S DISEASE and Acute Pancreatitis: A Bioinformatics and Systems Biology Approach

H Wu, T Su, M Zhi, J Yao - Journal of Crohn's and Colitis, 2024 - academic.oup.com
… most common pancreatic disease in inflammatory bowel disease (IBD) patients, with Crohn's
disease (CD) patients exhibiting significantly higher incidence than ulcerative colitis (UC) …

Inflammatory bowel disease pathogenesis: where are we?

C Fiocchi - Journal of gastroenterology and hepatology, 2015 - Wiley Online Library
… integrome” approach that takes advantage of all functional information derived from the
detailed investigation of each single pathogenic component through the use of systems biology

Systems analysis of inflammatory bowel disease based on comprehensive gene information

S Suzuki, T Takai-Igarashi, Y Fukuoka, DP Wall… - BMC Medical …, 2012 - Springer
… The rise of systems biology and availability of highly curated gene and molecular information
resources has promoted a comprehensive approach to study disease as the cumulative …

A systems pharmacology model for inflammatory bowel disease

V Balbas-Martinez, L Ruiz-Cerdá, I Irurzun-Arana… - PLoS …, 2018 - journals.plos.org
… in SPIDDOR R package [28], which allows translation of Boolean models (excluding
models enclosing temporal operators) to a standard Markup language in Systems Biology for …

The application of omics techniques to understand the role of the gut microbiota in inflammatory bowel disease

JP Segal, BH Mullish, MN Quraishi… - Therapeutic …, 2019 - journals.sagepub.com
… This review will focus on the use of systems biology technologies to better understand the
nature of microbial communities. We will summarize our knowledge to date regarding omics in …