… The search focused on studies describing or potentially describing diagnostic in vitro
methods in severe cutaneous adverse drug reactions. The entry terms used were “in vitro”, “…

… Type B reactions are idiosyncratic, immune-mediated and can lead to severe cutaneous
pathology.14 The type B reactions can be further segregated into different hypersensitivities …

… allopurinol can induce severe cutaneous adverse reactions (SCARs), including Stevens-Johnson
syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia …

… the rare but potentially severe cutaneous adverse reactions (SCARs) such as drug reactions
with … that the majority of the allopurinol-induced cutaneous reactions occurred in Asians 4 . …

… (MPE) to life-threatening severe cutaneous adverse drug reactions (SCARs), including drug
… abacavir-induced hypersensitivity reactions), drug-specific TCR clonotypes, T cell activation …

… -induced severe cutaneous adverse reactions and carbamazepine-tolerant controls. …
variables in cases of allopurinol and carbamazepine-induced severe cutaneous adverse reactions. …

… The most common CMV and EBV TCR clonotypes in the infusion product became the
most … In two additional cases (patient nos 1 and 8), acute skin GVHD developed prior to T-cell …

… Vancomycin is a commonly used antibiotic; however, it can cause life-threatening severe
cutaneous adverse reactions, such as drug reaction with eosinophilia and systemic symptoms (…

… Severe Cutaneous Adverse Reactions. Correlations … with a limited number of TCR clonotypes
shared by the patients and … Importantly, the VB-11 TCR clonotypes that permit the strongest …