Immunopathobiology and therapeutic targets related to cytokines in liver diseases

Y He, S Hwang, YA Ahmed, D Feng, N Li… - Cellular & molecular …, 2021 - nature.com
… Several cytokines have great therapeutic potential, and some are currently being tested as
therapeutic targets in clinical trials for the treatment of liver diseases, which are also described…

Immunological mechanisms and therapeutic targets of fatty liver diseases

H Wang, W Mehal, LE Nagy, Y Rotman - Cellular & Molecular …, 2021 - nature.com
cytokines to stimulate liver regeneration. Similarly, G-CSF improves the function of normal
and dysfunctional granulocytes, which also secrete cytokines to stimulate liver … against liver

Matrix metalloproteinases as potential biomarkers and therapeutic targets in liver diseases

E Geervliet, R Bansal - Cells, 2020 - mdpi.com
… MMPs in liver diseases. MMP expression patterns in different stages of liver diseases have
also … , we highlight MMPs as promising therapeutic targets for the resolution of liver diseases. …

[HTML][HTML] Therapeutic targeting of hepatic macrophages for the treatment of liver diseases

D van der Heide, R Weiskirchen, R Bansal - Frontiers in immunology, 2019 - frontiersin.org
… , which is reflected in a high diversity in released cytokines, cell surface markers and … could
be potential therapeutic targets to develop new therapies for the treatment of ALD (74, 76). …

Alcoholic liver disease: pathogenesis and new therapeutic targets

B Gao, R Bataller - Gastroenterology, 2011 - Elsevier
liver disease (ALD) is a major cause of chronic liver disease worldwide and can lead to
fibrosis and cirrhosis. … to identify therapeutic targets because serum levels of cytokines such as …

MicroRNAs as regulators, biomarkers and therapeutic targets in liver diseases

X Wang, Y He, B Mackowiak, B Gao - Gut, 2021 - gut.bmj.com
… the regulation and function of miRNAs in liver diseases with a major focus on miRNAs that
diseases and may identify biomarkers and therapeutic targets for liver diseases in the future…

[HTML][HTML] New advances in molecular mechanisms and emerging therapeutic targets in alcoholic liver diseases

JA Williams, S Manley, WX Ding - World journal of …, 2014 - ncbi.nlm.nih.gov
… study alcoholic liver disease and the detrimental factors that contribute to alcoholic liver disease
… lipid accumulation, inflammatory cytokine production and liver injury than wild type mice. …

Inflammation and liver cancer: molecular mechanisms and therapeutic targets

YM Yang, SY Kim, E Seki - Seminars in liver disease, 2019 - thieme-connect.com
… the role of cytokine signals, NF-κB, JNK, innate and adaptive immunity, and hepatic stellate
cells in HCC and discusses whether these pathways could be therapeutic targets. The …

Neutrophils in liver diseases: pathogenesis and therapeutic targets

K Liu, FS Wang, R Xu - Cellular & molecular immunology, 2021 - nature.com
liver disease, liver fibrosis, cirrhosis, liver failure, and liver … review summarizes the role of
neutrophils in liver diseases. … During liver cirrhosis, high levels of proinflammatory cytokines

[HTML][HTML] Immune imbalances in non-alcoholic fatty liver disease: from general biomarkers and neutrophils to interleukin-17 axis activation and new therapeutic targets

FC Paquissi - Frontiers in immunology, 2016 - frontiersin.org
… Finally, we reviewed the potential of these pathways as new therapeutic targets in NAFLD. …
family cytokines will be discussed further elsewhere in this paper. Similarly, TGF-β, a cytokine