… Several therapeutic targets regulating the lipid metabolism and innate immunity of NAFLD
… leads to the production of inflammatory cytokines and chemokines. These effector molecules …

… in the disease are capable of producing cytokines and … This review will discuss the roles of
key cytokines in different … our understanding of the roles of cytokines in the cellular processes …

… the IL-1 cytokine family in liver disease has been extensively studied (IL-1α, IL-1β, IL-33),
leading to strong arguments favoring these molecules as potential therapeutic targets, the role …

… disorders and they may be new potential therapeutic targets for obesity-related bone loss
[176, 177]. A number of clinical studies showed that most patients who suffer from RA or …

… The occurrence and development of LI may eventually lead to liver failure in time-… In addition,
inappropriate activation of NF-κB can lead to excessive release of inflammatory cytokines, …

… An important advance in our knowledge of liver diseases is … are therefore potential therapeutic
targets, including insulin … innate immunity, cytokine secretion and the gut–liver axis 4 . …

… production of several inflammatory cytokines through the early-… liver diseases there is no
doubt that TLRs, mainly TLR4, play a fundamental role in inflammation and fibrosis of the liver…

… IL-1β is a crucial cytokine promoting the inflammatory reaction in heart failure. Tet2 mutation
… IL-1β signaling in mice, and heart failure can be prevented by treating the mice with a …

… diseases through the abnormal secretion of adipocytokines. In this review, the importance
of adipocytokines, including adiponectin, is discussed with respect to atherosclerosis. …

… liver disease: a rising health threat Non-alcoholic fatty liver disease (NAFLD) comprises a
cluster of liver disorders … to its effects on inflammatory cytokines and hepatic stellate cells, and …