Cytokines in the pathogenesis of fatty liver and disease progression to steatohepatitis: implications for treatment
C Carter-Kent, NN Zein… - Official journal of the …, 2008 - journals.lww.com
… fatty liver disease (NAFLD) is currently the most common form of chronic liver disease, … of
these processes may help to identify novel therapeutic targets to treat this disease ( 6 ). A net …
these processes may help to identify novel therapeutic targets to treat this disease ( 6 ). A net …
Cytokines as therapeutic targets in SLE
L Rönnblom, KB Elkon - Nature Reviews Rheumatology, 2010 - nature.com
… cytokines. Consequently, the precise role of a single cytokine in human autoimmune diseases
… Despite this difficulty, targeting cytokines in many rheumatic diseases, such as rheumatoid …
… Despite this difficulty, targeting cytokines in many rheumatic diseases, such as rheumatoid …
Current and emerging therapeutic targets for IBD
MF Neurath - Nature Reviews Gastroenterology & Hepatology, 2017 - nature.com
… inflammatory pathways in other chronic inflammatory disorders Cytokine blockers (such as
ustekinumab and JAK inhibitors) suppressing cytokine signalling are probably a new addition …
ustekinumab and JAK inhibitors) suppressing cytokine signalling are probably a new addition …
Alcoholic liver disease: role of cytokines
MG Neuman, Y Maor, RM Nanau, E Melzer, H Mell… - Biomolecules, 2015 - mdpi.com
… topics dealing with alcoholic liver disease (ALD), including clinical and translational research.
It focuses on the role of the immune system and the signaling pathways of cytokines in the …
It focuses on the role of the immune system and the signaling pathways of cytokines in the …
New surprises of suppressor of cytokine signalling in liver fibrosis
C Cheng, C Huang, TT Ma, T Xu, YR Wang… - … Therapeutic Targets, 2014 - Taylor & Francis
… and SOCS3 are constitutively bound to, is a pivotal cytokine/chemokine generated by the
KCs in response to liver damage that induces inflammation, which is a contributing factor in …
KCs in response to liver damage that induces inflammation, which is a contributing factor in …
Cytokines: roles in atherosclerosis disease progression and potential therapeutic targets
… role cytokines play during disease progression … cytokines and their key roles in atherosclerosis
development they represent promising therapeutic targets in the treatment of this disease. …
development they represent promising therapeutic targets in the treatment of this disease. …
Current status of novel antifibrotic therapies in patients with chronic liver disease
M Cohen-Naftaly, SL Friedman - Therapeutic advances in …, 2011 - journals.sagepub.com
… and epigenetic regulation, represent fertile therapeutic targets. New therapies include drugs
… of cytokine and chemokine signaling become clearer, new potential therapeutic targets …
… of cytokine and chemokine signaling become clearer, new potential therapeutic targets …
Molecular signaling pathways and therapeutic targets in hepatocellular carcinoma
M Dimri, A Satyanarayana - Cancers, 2020 - mdpi.com
… , obesity, aflatoxin B1 (AFB1) exposure and nonalcoholic fatty liver disease (NAFLD) [4]. …
HGF is a multifunctional cytokine that has been implicated in the invasion of tumor malignancies …
HGF is a multifunctional cytokine that has been implicated in the invasion of tumor malignancies …
The hepatic microcirculation: mechanistic contributions and therapeutic targets in liver injury and repair
B Vollmar, MD Menger - Physiological reviews, 2009 - journals.physiology.org
… by liver diseases makes the technique an attractive tool for the measurement of hepatic …
to the role of this cytokine in liver injury, the pathogenic contribution of other proinflammatory …
to the role of this cytokine in liver injury, the pathogenic contribution of other proinflammatory …
Prognostic markers and putative therapeutic targets for hepatocellular carcinoma
M Frau, F Biasi, F Feo, RM Pascale - Molecular aspects of medicine, 2010 - Elsevier
… at identifying new putative prognostic markers and therapeutic targets of this tumor. Highest
c-myc … cycles of necrosis-liver regeneration foster a chronic liver disease leading to cirrhosis. …
c-myc … cycles of necrosis-liver regeneration foster a chronic liver disease leading to cirrhosis. …