… cancer from the perspective of cellular and molecular mechanisms and reported the therapeutic
targets of hepatocarcinoma, suggesting that antioxidants are urgently needed to prevent …

… liver diseases such as nonalcoholic fatty liver disease (… to the identification of several
therapeutic targets. In this Review, … inflammation through the production of inflammatory cytokines, …

… cytokines and chemokines as therapeutic targets in heart failure, We focus on the prototypic
inflammatory cytokines … contribution to dysfunction and heart failure progression. Finally, we …

… In this review we will focus on the role of pro-inflammatory cytokines and their inhibitors in
RA, and whether they may be causal in the accelerated atherosclerosis seen in these patients. …

… inform the design of novel therapeutic targets. Therefore, the … of chronic liver disease depends
on the degree of liver fibrosis. … lead to cirrhosis, liver failure, or liver cancer, in which liver …

… I cytokine pattern with high levels of IFN-γ, IL-5, IL-6, IL-10, IL-12 and IL-15 in the blood and
liver of … fibrosis that is typically associated with alcoholic liver disease and NAFLD. In these …

… Corticosteroids reduce mortality by acting on the hepatic-systemic inflammation. On the …
cytokines and stimulating anti-inflammatory cytokines as potential therapeutic targets in ALD. …

… limitations in the ability of IL10 to reverse established disease, limitations of IL10 as a global
… can also induce proinflammatory cytokines under certain conditions by certain cell types ( 36…

… disease (metabolism-associated liver disease, alcoholic … role of LSECs as therapeutic
targets for liver disease. Finally, … and anti-inflammatory cytokines and extracellular matrix (ECM) …

… cirrhosis. It remains a leading cause of morbidity and mortality in the US and worldwide. The
severity of liver disease … protect from alcohol-induced liver disease, bacterial translocation (…