… Boosted evidence with a deep understanding of IL-10 as a regulator of fibrosis has the
potential to unveil novel therapeutic targets, significantly enhancing outcomes and the quality of …

… therapeutic targets for prevention of inflammation-driven NAFLD progression. … of cytokines
has been recently shown to play an important role in pathogenesis of variety of liver diseases, …

… liver cancer and typically develops in the context of chronic liver disease and cirrhosis with
… Cancers are able to induce emergency granulopoiesis via the release of cytokines such as …

… inflammatory liver diseases and discuss a concise but comprehensive detail on the scope of
cytokine … processes, they serve as excellent therapeutic targets in diseases [107,108]. Since …

… Key cytokines and growth factors determining liver fibrosis regulate expression of profibrogenic
and antifibrogenic miRNAs (summarized elsewhere … MicroRNAs as therapeutic targets …

… of therapeutic targets for the discovery of drugs against specific diseases. This article is
intended to provide an overview of the progress in the exploration of therapeutic targets and to …

… cell activation and the inflammatory cytokine pathway [Citation42]… wide variety of inflammatory
cytokines in the liver [Citation12]. … increasingly become promising therapeutic targets in the …

… injury, which if persistent leads to cirrhosis and liver failure. … of ECM in liver fibrosis; (iii)
elucidation of key cytokines, their … genes that can be used as therapeutic targets? (iv) What is the …

Despite considerable progress elucidating the cellular and molecular events associated
with chronic inflammatory bowel diseases (IBD), the etiology of Crohn’s disease (CD) and …

… cytokines (eg, IL‐1β 94 ) and protected mice from liver fibrosis. The metabolic and anti‐inflammatory
effects of PPAR‐δ agonists make them attractive therapeutic targets in NASH. …