Effects of 17 α-methyltestosterone on transcriptome, gonadal histology and sex steroid hormones in rare minnow Gobiocypris rarus

J Gao, S Liu, Y Zhang, Y Yang, C Yuan, S Chen… - … and Physiology Part D …, 2015 - Elsevier
… by which MT causes adverse effects in fish, transcriptome profiling of gonads, gonadal
histology and the sex steroid hormones in response to MT were analyzed in Gobiocypris rarus. …

[HTML][HTML] Effects of 17α-Methyltestosterone on the Transcriptome and Sex Hormones in the Brain of Gobiocypris rarus

S Liu, Y Chen, T Li, L Qiao, Q Yang, W Rong… - International Journal of …, 2023 - mdpi.com
… 17α-Methyltestosterone (MT), a synthetic environmental endocrine disruptor with … system
and inhibit germ cell maturation in Gobiocypris rarus. To further investigate the regulation of …

Gonadal development and transcript profiling of steroidogenic enzymes in response to 17α-methyltestosterone in the rare minnow Gobiocypris rarus

S Liu, L Wang, F Qin, Y Zheng, M Li, Y Zhang… - The Journal of steroid …, 2014 - Elsevier
… Rare minnow Gobiocypris rarus was used as model fish in the present study. G. rarus is a
Chinese freshwater cyprinid, endemic to the upstream of Yangze River, Sichuan Province, …

[HTML][HTML] Integrated Analysis of mRNA- and miRNA-Seq in the Ovary of Rare Minnow Gobiocypris rarus in Response to 17α-Methyltestosterone

S Liu, Q Yang, Y Chen, Q Liu, W Wang, J Song… - Frontiers in …, 2021 - frontiersin.org
… The objective of this study was to explore the effects of exogenous MT on the growth and
gonadal development of female rare minnow Gobiocypris rarus. Female G. rarus groups were …

[HTML][HTML] Comparative Analysis of miRNA-mRNA Regulation in the Testes of Gobiocypris rarus following 17α-Methyltestosterone Exposure

S Liu, J Zhou, Q Yang, Y Chen, Q Liu, W Wang… - International Journal of …, 2023 - mdpi.com
… , male Gobiocypris rarus were exposed to 25, 50, and 100 ng/L of 17α-methyltestosterone
(… rarus in the MT exposure and control groups. We found that there were more mature sperm (…

… , pregnane X receptor, two cytochrome P450s and five phase II metabolism genes responsive to 17alpha-methyltestosterone in rare minnow Gobiocypris rarus

J Gao, S Liu, Y Zhang, C Yuan, Y Yang… - Environmental Toxicology …, 2014 - Elsevier
… in both genders adult rare minnow Gobiocypris rarus. The present findings suggest that AHR2
rarus. Additionally, UGT2A1 may make greater contribution than SULT1 ST4 and SULT1 …

Responses of gonadal transcriptome and physiological analysis following exposure to 17α-ethynylestradiol in adult rare minnow Gobiocypris rarus

J Gao, Y Zhang, T Zhang, Y Yang, C Yuan, J Jia… - Ecotoxicology and …, 2017 - Elsevier
… Rare minnow Gobiocypris rarus is a native freshwater cyprinid fish in Yangtze River, Sichuan
Province, China. It is an attractive laboratory animal in aquatic toxicity tests because of its …

Transcriptome profiling analysis of rare minnow (Gobiocypris rarus) gills after waterborne cadmium exposure

ZJ Wang, XH Liu, L Jin, DY Pu, J Huang… - … and Physiology Part D …, 2016 - Elsevier
… Rare minnow (Gobiocypris rarus) is a widely used experimental fish in risk assessments of
aquatic pollutants in China. Cadmium (Cd) is one of the most toxic heavy metals in the world; …

Toxicogenomic applications of Chinese rare minnow (Gobiocypris rarus) in aquatic toxicology

X Liang, J Zha - Comparative Biochemistry and Physiology Part D …, 2016 - Elsevier
… In summary, Chinese rare minnow (Gobiocypris rarus) is an excellent model for chemical
safety assessment and environmental toxicological studies. With the development of …

The secretion, synthesis, and metabolism of cortisol and its downstream genes in the H–P–I axis of rare minnows (Gobiocypris rarus) are disrupted by acute …

XH Liu, BW Xie, ZJ Wang, L Jin, YG Zhang - Comparative Biochemistry and …, 2016 - Elsevier
… To deeply explore the effects and related mechanism of Cd on the H–P–I, we used the rare
minnow (Gobiocypris rarus) as a model fish in the present study. The rare minnow is a small …