… and properties of α-synuclein aggregates in vitro and in vivo. One … on the aggregation kinetics
of α-synuclein in vitro using … steps in the aggregation of α-synuclein in the absence of any …

… in vitro and in vivo experimental models mimicking α-synuclein pathology such as oligomerization,
toxicity and … of molecules capable of modulating α-synuclein toxicity. Here, we review …

… able to detect E46K-induced α-syn aggregates and toxicity. … aggregates both in vitro and
in cell cultures, and resulted in cell death. Baicalein decreased E46K α-syn aggregation in vitro …

… These aggregates may be uptaken and propagated … of α-synuclein aggregation in vitro,
as well as crucial factors affecting this process. We also describe how PD-linked α-synuclein …

… induced toxicity in human H4 neuroglioma cells. Here, we hypothesize that GA treatment
will reduce α-synuclein aggregation and prevent α-synuclein induced toxicity and we show that …

… , α-synuclein, and mutant Huntingtin which participate in the formation, accumulation,
and deposition of toxic misfolded aggregates… inhibit aggregation of amyloid β, tau, and α-synuclein …

… the potential neurotoxic effects of -synuclein aggregation and might help in … synuclein
fragment NAC was neurotoxic and selectively induced DA neurodegeneration in vitro and in vivo…

… α-synuclein in an α-synuclein transgenic mouse model and in an in vitro model of α-synuclein
aggregation… Hsp70 into the in vivo model by breeding α-synuclein transgenic mice with …

… structure, aggregation, fibril formation, and membrane binding of monomeric α-Syn in vitro
using … (CD), and a battery of imaging and aggregation assays. To determine how this mutation …

… quantitative in vitro assays, we identify a compound, squalamine, that blocks α-synuclein
aggregation, … Our results show that squalamine, by competing with α-synuclein for binding lipid …