… , role in lysosomal dysfunction and activation of the … recent evidence linking α-synuclein
and mitochondrial dysfunction in … between α-synuclein and mitochondrial dysfunction may …

… α-Synuclein (SNCA) is a substantive component of Lewy bodies, … , mitochondrial dysfunction
and impaired regulation of protein turnover interact to cause dopaminergic cell dysfunction …

… a link between α-synuclein deposition and the onset of impaired mitochondrial homeostasis,
… This suggests that both α-synuclein pathology and mitochondrial impairment may very well …

… mitochondrial complex I activity assay by ELISA confirmed a 40% inhibition specifically in the
ventral midbrain. Mitochondrial dysfunction … synuclein. Thus, in mice over-expressing alpha-…

… Previously, most of the studies focused on the mitochondrial dysfunction … mitochondrial
dysfunction modulates α-synuclein aggregation or α-synuclein causes mitochondrial dysfunction. …

Chronic systemic complex I inhibition caused by rotenone exposure induces features of
Parkinson's disease (PD) in rats, including selective nigrostriatal dopaminergic degeneration …

… Mitochondria are remarkably … on mitochondrial dysfunction-mediated alpha-synuclein
aggregation. We highlight some of the findings that provide proof of evidence for a mitochondrial …

… mitochondrial pathology in PD (39, 40). However, the neurotoxic mechanisms underlying
mitochondrial dysfunction … the deposition of abnormal α-syn and mitochondrial damage has not …

… To test the presence of α synuclein in mitochondria of dopaminergic neurons of PD brains,
we carried out using triple immuno staining on deparaffinised tissue sections from …

… α-Syn-induced mitochondrial toxicity. We show that α-Syn causes mitochondrial dysfunction
… We present evidence showing that oxidative stress and impaired mitochondrial function are …