… Meanwhile, NLRP3 inflammasome was found to be activated … between α-synuclein and
NLRP3 inflammasome to provide a … α-Synuclein, focusing on the correlation studies between α-…

… to activate the NLRP3 inflammasome of microglia through … role of the α-syn/TLRs/NF-κB/NLRP3
inflammasome axis and … on the α-syn/TLRs/NF-κB/NLRP3 inflammasome axis of …

… to α-synuclein transmission from neuron to neuron. Furthermore, we propose a model of
microglial NLRP3 inflammasome-dependent exosome secretion and exosomal α-synuclein …

… The important question of how α-syn might influence NLRP3 inflammasome … that α-syn fibrils
can activate the NLRP3 inflammasome in primary human microglia, inducing inflammasome…

… activate the NLRP3 inflammasome independent of an LPS priming step. Unprimed WT
microglia were treated with αSyn alone or in combination with the NLRP3 inflammasome inhibitor …

… of α-synuclein (… (NLRP3) inflammasome in human microglia and whether anti-αSyn antibodies
could prevent this effect. Here, we show that αSyn activates the NLRP3 inflammasome in …

… NLRP3 inflammasome is activated in the PBMCs from PD patients. The related inflammatory
cytokine IL-1β and total α-synuclein … Furthermore, plasma α-synuclein levels have a positive …

… whether structurally different α-syn polymorphs induce the NLRP3 inflammasome in
microglia, we exposed primary mouse microglia to well-characterized recombinant human α-syn …

… In this study, astrocytes from mouse brain tissue were extracted for testing, and we found
that α-synuclein could activate NLRP3 inflammasome through autophagy signaling pathway …

… α-synuclein pathology were assessed by IHC and immunofluorescence. Our results show
that NLRP3 inflammasome inhibition via NLRP3 … nigral pathological α-synuclein formation in …