… Activation of opioid receptors or bradykinin receptors stimulates the formation of a cytoplasmic
complex containing MDM2, β-arrestin 2 and the receptor, which retains MDM2 in the …

… –βarr complex is essential for functional outcomes or partially engaged complex can also …
Here we assemble partially and fully engaged complexes of a chimeric β 2 V 2 R with βarr1, …

… on these findings, we propose a functional model of arrestin-dependent regulation of MAPK
activity and a new structural model of the arrestin-MAPK multiprotein signaling complex. …

… ) signaling and related behaviors in mice by disrupting a signaling complex composed of
Akt, β-arrestin … When administered to β-arrestin 2 knockout mice, lithium fails to affect Akt/GSK3 …

… member of the signaling complex is Erk. Erk1 showed a clear preference for the Mek binding
site in both β-arrestins. We therefore decided to dock Erk1 on the complex β-arrestin 1/Mek1…

… 2 (ERK1/2) pathway, forming unique signaling modules. The aim of this review is to analyze
… signaling features of the multi-protein complex GPCR-β-arrestin-ERK1/2, a unique signaling …

… the formation of signaling complexes containing β-arrestin 2, PP2A, and Akt. β-arrestin 2 …
mediated dopamine-receptor signaling is not inhibited in the absence of β-arrestin 2. These …

… β-arrestin binds to and forms a trimeric complex with axin and Dvl. Moreover, endogenous
β-arrestin … for proper activation of Dvl, signaling along the Wnt/β-catenin pathway, activation of …

… strongly suggest that β-arrestin-2, Akt and Src form a complex in vivo and that β-arrestin-2
is … Next, we examined whether the formation of this Akt/β-arrestin-2/Src signalling complex …

… (50) described an agonist-induced β-arrestin2, Raf-1, MEK1, and ERK1/2 signaling complex…
in the complex (77). This is the first report of a negative regulator in a β-arrestin signaling …