… BCRP is the primary cause of expulsion of lipophilic chemotherapeutic agents from the
tumor cells. The cells eventually develop resistance against such chemotherapeutic agents …

… various β-carbolines as potential anticancer agents, … β-carbolines as anticancer agents
for readers, this review provides a comprehensive summary of anticancer activities of β-carboline …

… novel chemotherapeutic agents. In this regard, we have reviewed the development of β-carboline-based
chemotherapeutic agents … on the molecular hybrids of β-carbolines with various …

… spectrum of anticancer activities through … -β-carboline derivatives as potent antitumor
agents via inhibition of both topoisomerase-I and KSP. For further optimization to get anticancer …

… β-carbolines (a), a novel therapeutic anticancer agent has a vital importance. It is an indole
alkaloid which is isolated from the natural source Peganum harmala, having planer tricyclic …

… β-carboline derivatives can be used as lead compounds for developing novel antitumor
agents… 3 and 9 of the β-carboline nucleus augments antitumor activity and reduces acute toxicity.…

… relationship of β-carboline derivatives as antitumor agents, in … It was proved that substituent
in position-9 of the β-carboline ring … a novel antitumor drug that could surpass Adriamycin. …

… Additionally, the severe side effects of synthetic anticancer drugs, as well as a rapid emergence
of … Anticancer drugs exert their cytotoxic roles through different mechanisms in modifying …

… of bivalent β-carbolines may lead to the discovery of novel antitumor agents. Accordingly,
in the present study, we synthesized bivalent β-carbolines and tested their antitumor activities …

… related amino acid linked β-carboline derivatives, which … β-carboline derivatives as DNA
interactive topo II inhibitors with apoptosis ability [23a]. In search for newer anticancer agents …