Aberrant Wnt/β-catenin pathway activation in idiopathic pulmonary fibrosis

…, S Pedron, M Bertaso, A Scarpa, B Murer… - The American journal of …, 2003 - Elsevier
… of Wnt/β-catenin aberrant activation in IPF/UIP. In this study nuclear β-catenin accumulation
… , 3, 4, 16 According to our study, the aberrant activation of the Wnt pathway was particularly …

Aberrant Wnt/β-catenin signaling in pancreatic adenocarcinoma

G Zeng, M Germinaro, A Micsenyi, NK Monga, A Bell… - Neoplasia, 2006 - Elsevier
aberrant activation is associated with several cancers. The aim of this study is to examine the
Wnt/B-catenin … Because we demonstrate aberrant Wnt/b-catenin activation in around 65% …

Control of βcatenin signaling in tumor development

J Behrens - Annals of the New York Academy of Sciences, 2000 - Wiley Online Library
aberrantly activated. The wnt signal is transmitted to the nucleus by the cytoplasmic component
β-catenin: in the absence of wnts, β-catenin … presence of wnts β-catenin is stabilized and …

Ras stabilization through aberrant activation of Wnt/β-catenin signaling promotes intestinal tumorigenesis

WJ Jeong, J Yoon, JC Park, SH Lee, SH Lee… - Science …, 2012 - science.org
… are aberrant activation of the Ras-MAPK and Wnt/β-catenin signaling pathways (9). The
Wnt/β-catenin … In a resting state, β-catenin interacts with the destruction complex, including the …

[HTML][HTML] WNT/β-catenin signaling in hepatocellular carcinoma: The aberrant activation, pathogenic roles, and therapeutic opportunities

A Gajos-Michniewicz, M Czyz - Genes & Diseases, 2024 - Elsevier
activated WNT/β-catenin signaling in HCC. We discuss the pivotal roles of CTNNB1 mutations,
aberrantly … of crosstalk between WNT/β-catenin signaling and other signaling pathways …

[HTML][HTML] Regulation of MYC gene expression by aberrant Wnt/β-catenin signaling in colorectal cancer

S Rennoll, G Yochum - World journal of biological chemistry, 2015 - ncbi.nlm.nih.gov
… Instead, MYC is overexpressed due to aberrant activation of upstream signaling pathways
or due to events that trigger amplification of the MYC gene locus or insertions of activating

Role of a BCL9-related β-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling

…, S Ohwada, Y Omori, S Sugano, B Ohkawara… - Cancer research, 2004 - AACR
… protein, B9L, interacts with β-catenin and enhances β-catenin-TCF–mediated transcription.
… for β-catenin–induced transformation of RK3E cells and that expression of B9L is aberrantly

Aberrant activation of the WNT/β-catenin signaling pathway in lupus nephritis

X Wang, X Huang, Q Yan, C Bao - PLoS One, 2014 - journals.plos.org
… The canonical WNT/β-catenin signaling pathway was activated in lupus nephritis patients,
accompanied by an increase in plasma levels of Dkk-1. Altered WNT/β-catenin signaling was …

[HTML][HTML] Aberrant activation of hedgehog signaling pathway contributes to endometrial carcinogenesis through β-catenin

X Liao, MKY Siu, CWH Au, QKY Chan, HY Chan… - Modern Pathology, 2009 - Elsevier
Aberrant activation of hedgehog pathway may play important roles in endometrial cancer
through β-cateninAberrant activation of the hedgehog signaling pathway has been described …

[HTML][HTML] Aberrant activation of Wnt/β-catenin signaling drives proliferation of bone sarcoma cells

C Chen, M Zhao, A Tian, X Zhang, Z Yao, X Ma - Oncotarget, 2015 - ncbi.nlm.nih.gov
… , whereas downregulation of activated Wnt signaling with dnTCF4 … evidence that aberrant
activation of Wnt/β-catenin pathway … the autocrine activation of the Wnt/β-catenin signaling as a …