WNT–β-catenin signalling—a versatile player in kidney injury and repair
SJ Schunk, J Floege, D Fliser, T Speer - Nature Reviews Nephrology, 2021 - nature.com
… disease (CKD), podocyte injury and proteinuria, acute kidney injury (AKI), cystic kidney …
understanding of WNT–β-catenin signalling and its regulation during kidney injury, as well …
understanding of WNT–β-catenin signalling and its regulation during kidney injury, as well …
Wnt/β-catenin in acute kidney injury and progression to chronic kidney disease
T Huffstater, WD Merryman, LS Gewin - Seminars in nephrology, 2020 - Elsevier
… We review the role of Wnt/β-catenin in renal injury with a … this signaling occurs independent
of the β-catenin–dependent (ie, … Wnt/β-catenin signaling pathway in the context of renal injury …
of the β-catenin–dependent (ie, … Wnt/β-catenin signaling pathway in the context of renal injury …
[HTML][HTML] Wnt/β-catenin signaling in kidney injury and repair: a double-edged sword
D Zhou, RJ Tan, H Fu, Y Liu - Laboratory investigation, 2016 - Elsevier
… Re-activation of Wnt/β-catenin underscores that this developmental … of injury in adult
kidney. A comprehensive understanding of Wnt/β-catenin regulation and its roles in kidney injury …
kidney. A comprehensive understanding of Wnt/β-catenin regulation and its roles in kidney injury …
[HTML][HTML] Role changes of β-catenin in kidney injury and repair
J Peng, Z Dong - Kidney international, 2012 - Elsevier
… Moreover, continuous activation of β-catenin may lead to renal fibrosis. Further investigation
… played by β-catenin and related signaling in kidney injury, repair, and fibrosis. β-catenin and …
… played by β-catenin and related signaling in kidney injury, repair, and fibrosis. β-catenin and …
[HTML][HTML] Wnt/β-catenin signaling mediates both heart and kidney injury in type 2 cardiorenal syndrome
Y Zhao, C Wang, X Hong, J Miao, Y Liao, FF Hou… - Kidney international, 2019 - Elsevier
… role of β-catenin activation triggered by TAC serum in mediating kidney injury, we knocked
down β-catenin … As shown in Figure 6f–k, knockdown of β-catenin inhibited its activation and …
down β-catenin … As shown in Figure 6f–k, knockdown of β-catenin inhibited its activation and …
Blockade of Wnt/β-catenin signaling by paricalcitol ameliorates proteinuria and kidney injury
W He, YS Kang, C Dai, Y Liu - Journal of the American Society of …, 2011 - journals.lww.com
… dysfunction, proteinuria, and kidney injury by modulating Wnt/β-catenin signaling. …
kidney injury by inhibiting Wnt/β-catenin signaling. These studies indicate that blocking Wnt/β-catenin …
kidney injury by inhibiting Wnt/β-catenin signaling. These studies indicate that blocking Wnt/β-catenin …
(Pro) renin receptor is an amplifier of Wnt/β-catenin signaling in kidney injury and fibrosis
Z Li, L Zhou, Y Wang, J Miao, X Hong… - Journal of the …, 2017 - journals.lww.com
… PRR can promote kidney injury and fibrosis by amplifying Wnt/β-catenin signaling. … kidney
injury, we studied three animal models of CKD induced by renal ischemia/reperfusion injury (…
injury, we studied three animal models of CKD induced by renal ischemia/reperfusion injury (…
[HTML][HTML] Tubule-specific ablation of endogenous β-catenin aggravates acute kidney injury in mice
D Zhou, Y Li, L Lin, L Zhou, P Igarashi, Y Liu - Kidney international, 2012 - Elsevier
… of renal β-catenin in mouse model of acute kidney injury induced by folic acid. (a, b)
Immunohistochemical staining shows the expression and localization of β-catenin in the kidneys at 2 …
Immunohistochemical staining shows the expression and localization of β-catenin in the kidneys at 2 …
[HTML][HTML] Wnt/β-catenin regulates blood pressure and kidney injury in rats
L Xiao, B Xu, L Zhou, RJ Tan, D Zhou, H Fu, A Li… - … Et Biophysica Acta (BBA …, 2019 - Elsevier
… speculate that Wnt/β-catenin could promote BP elevation and kidney injury by the virtue of …
Wnt/β-catenin signaling by a range of approaches is able to ameliorate kidney fibrotic lesions …
Wnt/β-catenin signaling by a range of approaches is able to ameliorate kidney fibrotic lesions …
[HTML][HTML] Wnt/β-catenin links oxidative stress to podocyte injury and proteinuria
L Zhou, X Chen, M Lu, Q Wu, Q Yuan, C Hu, J Miao… - Kidney international, 2019 - Elsevier
… Wnt/β-catenin is an evolutionarily conserved signal pathway that plays a … injury repair.19,
20, 21 Wnt/β-catenin signaling is silent in normal adults but is reactivated after kidney injury in a …
20, 21 Wnt/β-catenin signaling is silent in normal adults but is reactivated after kidney injury in a …
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