Wnt/beta-catenin and PI3K/Akt/mTOR signaling pathways in glioblastoma: two main targets for drug design: a review
SH Shahcheraghi, V Tchokonte-Nana… - Current …, 2020 - ingentaconnect.com
… were used to treat U87 cells to establish the correlation … by inhibition of Wnt/βcatenin
signaling. Mol Carcinog 2018; … phenotype in microglial cells through Wnt/β-catenin signaling. …
signaling. Mol Carcinog 2018; … phenotype in microglial cells through Wnt/β-catenin signaling. …
Tetrandrine inhibits glioma stem-like cells by repressing β-catenin expression
Y Zhang, YL Wen, JW Ma, JC Ye… - International …, 2017 - spandidos-publications.com
… , we activated β-catenin by treating U87 GSLCs and U251 GSLCs cells with the GSK3β … or
we inactivated β-catenin/TCF transcription by treating U87 GSLCs and U251 GSLCs cells with …
we inactivated β-catenin/TCF transcription by treating U87 GSLCs and U251 GSLCs cells with …
The positive correlation between DJ‐1 and β‐catenin expression shows prognostic value for patients with glioma
… β-catenin and p-Akt, and negatively correlated with PTEN expression … U87, U251 MG,
SWO-38 and SHG44 human glioma cell lines. After the knockdown of DJ-1, Akt, p-Akt or β-catenin …
SWO-38 and SHG44 human glioma cell lines. After the knockdown of DJ-1, Akt, p-Akt or β-catenin …
ICAT inhibits glioblastoma cell proliferation by suppressing Wnt/β-catenin activity
… the cellular distribution of β-catenin by immunofluorescence. U87 and U251 glioma cells …
results have shown that si-β-catenin inhibits the cell viability and invasive ability and induces …
results have shown that si-β-catenin inhibits the cell viability and invasive ability and induces …
… noncoding RNA papillary thyroid carcinoma susceptibility candidate 3 (PTCSC3) inhibits proliferation and invasion of glioma cells by suppressing the Wnt/β-catenin …
S Xia, R Ji, W Zhan - BMC neurology, 2017 - Springer
… LncRNA PTCSC3 overexpression inhibits the migration and invasion of U87 cells. a
Wound healing assay was used to determine the migration ability of U87 cells with or without …
Wound healing assay was used to determine the migration ability of U87 cells with or without …
[HTML][HTML] Trichosanthin suppresses the proliferation of glioma cells by inhibiting LGR5 expression and the Wnt/β-catenin signaling pathway
…, D Wang, J Zhou, C Fan, F Jiao, B Liu… - Oncology …, 2015 - spandidos-publications.com
… the change in cell viability of U87 cells after … cells treated with PBS alone, U87 cells treated
for 24 h exhibited viabilities of 97.7, 88.7, 78.6, 62.1, 36.2 and 27.3%, respectively, U87 cells …
for 24 h exhibited viabilities of 97.7, 88.7, 78.6, 62.1, 36.2 and 27.3%, respectively, U87 cells …
PCDH8 inhibits glioma cell proliferation by negatively regulating the AKT/GSK3β/β‑catenin signaling pathway
Z Zong, H Pang, R Yu, Y Jiao - Oncology Letters, 2017 - spandidos-publications.com
… U251 and U87 cells expressed decreased levels of PCDH8 compared with that of normal …
, and U87 and U251 cells. (B) Western blot of PCDH8 protein expression in U87 cells following …
, and U87 and U251 cells. (B) Western blot of PCDH8 protein expression in U87 cells following …
Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal …
… 2B) highlighted by strongest upregulation the case of U87 cell line. This corresponded to
intranuclear β-catenin localization in immunostaining of cells transfected with mutant β-catenin (…
intranuclear β-catenin localization in immunostaining of cells transfected with mutant β-catenin (…
Presenilin1 exerts antiproliferative effects by repressing the Wnt/β-catenin pathway in glioblastoma
W Yang, P Wu, J Ma, M Liao, L Xu, M Xu… - Cell Communication and …, 2020 - Springer
… Next, we detected the phosphorylation of β-catenin and GSK-3β in U87 and U251 cells.
The results showed that the Ser45 site and Thr41/Ser37/Ser33 site phosphorylation levels of …
The results showed that the Ser45 site and Thr41/Ser37/Ser33 site phosphorylation levels of …
Casein kinase 2α regulates glioblastoma brain tumor-initiating cell growth through the β-catenin pathway
RT Nitta, S Gholamin, AH Feroze, M Agarwal… - Oncogene, 2015 - nature.com
… whether the β-catenin is a major signaling pathway by which CK2α can regulate GBM
tumorigenesis, we stably transduced β-catenin in U87 shCK2α and U138 shCK2α cell lines. We …
tumorigenesis, we stably transduced β-catenin in U87 shCK2α and U138 shCK2α cell lines. We …