AKT inhibitor SC66 inhibits proliferation and induces apoptosis in human glioblastoma through down-regulating AKT/β-catenin pathway
… U87 and U251 cell proliferation and EMT- mediated cell … cells in vivo and in vitro by
deregulated AKT/β-catenin pathway. We also demonstrated that SC66 inhibited EMT-mediated cell …
deregulated AKT/β-catenin pathway. We also demonstrated that SC66 inhibited EMT-mediated cell …
β-Catenin induces transcriptional expression of PD-L1 to promote glioblastoma immune evasion
L Du, JH Lee, H Jiang, C Wang, S Wang… - Journal of Experimental …, 2020 - rupress.org
… S552A mutant reduced Wnt3A- and EGF-induced and CD274 promoter-mediated luciferase
activity and the binding of β-catenin to this promoter region in U87/EGFR cells (Fig. 3, F and …
activity and the binding of β-catenin to this promoter region in U87/EGFR cells (Fig. 3, F and …
Verbascoside inhibits progression of glioblastoma cells by promoting Let‐7g‐5p and down‐regulating HMGA2 via Wnt/beta‐catenin signalling blockade
WQ Jia, JW Zhu, CY Yang, J Ma, TY Pu… - Journal of Cellular …, 2020 - Wiley Online Library
… in U87 cells after transfection; E, apoptosis rate of U87 cells transfected with let-7g-5p mimic,
let-7g-5p inhibitor alone or in the presence of VB; F, apoptosis rate of U87 cells transfected …
let-7g-5p inhibitor alone or in the presence of VB; F, apoptosis rate of U87 cells transfected …
[PDF][PDF] Long non-coding RNA SUMO1P3 promotes glioma progression via the Wnt/β-catenin pathway.
JY Lou, J Luo, SC Yang, GF Ding… - European Review for …, 2020 - europeanreview.org
… eration and invasion of glioma cells, respectively. Furthermore, … , migration and invasion of
U87 and U251 cells. In addition, … active β-catenin, C-myc, and cyclin D1 in U87 and U251 cells…
U87 and U251 cells. In addition, … active β-catenin, C-myc, and cyclin D1 in U87 and U251 cells…
Lipid phosphate phosphatase-3 regulates tumor growth via β-catenin and Cyclin-D1 signaling
I Chatterjee, JO Humtsoe, EE Kohler, C Sorio… - Molecular Cancer, 2011 - Springer
… primary tumors and in U87 and U118 glioblastoma cell lines. We demonstrate that LPP3-knockdown
inhibited both U87 and U118 glioblastoma cell proliferation in culture and tumor …
inhibited both U87 and U118 glioblastoma cell proliferation in culture and tumor …
PELP1 promotes glioblastoma progression by enhancing Wnt/β-catenin signaling
GR Sareddy, UP Pratap… - Neuro-Oncology …, 2019 - academic.oup.com
… U87 cells … U87-control siRNA vs U87-PELP1 siRNA cells revealed the downregulation
of genes related to inhibition of matrix metalloproteases, glioma invasion signaling, Wnt/β-catenin …
of genes related to inhibition of matrix metalloproteases, glioma invasion signaling, Wnt/β-catenin …
[HTML][HTML] miR-188 inhibits glioma cell proliferation and cell cycle progression through targeting β-catenin
N Li, H Shi, LU Zhang, X Li, L Gao, G Zhang… - Oncology …, 2018 - ncbi.nlm.nih.gov
… -188 expression in the glioma cell lines H4, U87, SNB, and … cell proliferation and cell cycle
in glioma cells, and β-catenin … knocked down β-catenin expression in glioma LN229 cells by …
in glioma cells, and β-catenin … knocked down β-catenin expression in glioma LN229 cells by …
miR-126-3p sensitizes glioblastoma cells to temozolomide by inactivating Wnt/β-catenin signaling via targeting SOX2
W Luo, D Yan, Z Song, X Zhu, X Liu, X Li, S Zhao - Life sciences, 2019 - Elsevier
… -resistant GBM cells by exposing U87 and U251 cells (normally … U87 cells, the TMZ
concentration to decrease cell viability to 50% was about 53.28 μM (IC50 = 53.28); for U87/TR cells …
concentration to decrease cell viability to 50% was about 53.28 μM (IC50 = 53.28); for U87/TR cells …
SOX7 is associated with the suppression of human glioma by HMG-box dependent regulation of Wnt/β-catenin signaling
…, H Yang, Y Tian, Q Xie, Y Lu, Y Wang, N Su, B Dong… - Cancer letters, 2016 - Elsevier
… HMG-transfected U87 cells, and the other side was injected with mock transfected U87 cells.
… with mock-transfected U87 cells or SOX7△HMG-transfected U87 cell injection after 7 days. …
… with mock-transfected U87 cells or SOX7△HMG-transfected U87 cell injection after 7 days. …
[HTML][HTML] … -mediated silencing of microRNA-211 promotes cell growth and epithelial to mesenchymal transition through activation of the AKT/β-catenin pathway in GBM
W Li, X Miao, L Liu, Y Zhang, X Jin, X Luo, H Gao… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… U87 cells that stably expressed miR-211 and named these cells LV-miR-211, cells used as
… The MTT assay revealed that LV-miR-211 cells grew more slowly than the LV-control cells (…
… The MTT assay revealed that LV-miR-211 cells grew more slowly than the LV-control cells (…