… models, increased islet IL-1β expression and increased numbers of islet … islet inflammatory
process in the GK rat, showing increased islet expression of IL-1β and other pro-inflammatory …

… Inflammation is the body’s protective response to … that islet inflammation is a feature of type
2 diabetes, and discuss its role with respect to α and β cell compensation and eventual β cell …

… islet inflammation and β cell dysfunction in T2D, with a focus on the regulation of … β cell
dysfunction in T2D. Expanding our understanding of the cells that mediate islet inflammation may …

… -induced β-cell apoptosis by increasing β-cell secretion. The specific TLR2 receptor agonist
Pam2 induced IL1b, IL6, and IL8 expression in human islets and purified human β cells [34]. …

… of apoptotic beta cells [8]. As for the role of other cells taking part in islet inflammation, the
number of CD45 + leucocytes was higher within type 2 diabetic islets with preserved insulin …

… islets (Ehses et al. 2007; Homo-Delarche et al. 2006). Yet the nature of islet inflammation
and its impact on β cell … The present review will thus explore the role of islet inflammation and …

… fate and tissue inflammation not only in T1D or T2D but also in diverse types … cell death
and cell death-associated inflammation in regulating the mass and function of pancreatic β-cells …

… islet function and that cytokines are deleterious for -cells, we suggest that endothelial-islet
inflammation might contribute to -cell … treatments that preserve islet architecture and ameliorate …

… cellular and organ dysfunction; in beta cells, GSIS is impaired [24,25,26]. Islet and beta cells
can initiate islet inflammation … cytokines, chemokines and islet amyloid peptide (IAPP) to …

… processes are also activated in pancreatic islets from obese animals and humans with … of
immune cell-mediated inflammation in islets and the consequences of this with respect to β-cell …