Review of the use of dopamine transporter imaging agent 11C-β-CFT for diagnosing Parkinson disease

H Li, X Zhang, J Zhang - Int J Radiat Med Nucl Med, 2016 - ijrmnm.com
… drugs; therefore, 11C鄄茁鄄CFT is a favorable 孕耘栽 imaging agent for DAT. 11C鄄茁鄄…
Dopamine transporter imaging agent 11C鄄CFT and 18F鄄CFT and its clinical application …

Dopamine transporter imaging agent 11C-CFT and 18F-CFT and its clinical application development

C Li-ming, Y Xiao-feng, W Shuang, WU Jun… - Int J Radiat Med Nucl …, 2009 - ijrmnm.com
CFT和18F.cvr PET均被用于临床早期诊断帕金森病和对药物… Dopamine transporter imaging
agent nC-CFT and 1智-CFT … 通过评价纹状体多巴胺转运体(dopamine transporter,DAT)浓度是…

[18F]CFT ([18F]WIN 35,428), a radioligand to study the dopamine transporter with PET: Biodistribution in rats

M Haaparanta, J Bergman, A Laakso, J Hietala… - Synapse, 1996 - Wiley Online Library
… Pretreatment of the rats with a specific dopamine transport inhibitor, GBR 12909, showed
that CFT binding is specific in striatum. The highest accumulation of 18F-radioactivity was …

The preclinical pharmacological study of dopamine transporter imaging agent 18F-FP-β-CIT

LI Xiaomin, C Zhengping, W Songpei, T Jie… - Nuclear Science and …, 2007 - Elsevier
… carbomethoxy-3P- (4-iodopheny1)nortropane) as an imaging agent for dopamine transporter
The uptake in striaturn can be blocked by P-CFT, suggesting that "F-FP-P-CIT binds to DAT …

[18F]CFT synthesis and binding to monoamine transporters in rats

S Forsback, P Marjamäki, O Eskola, J Bergman… - EJNMMI research, 2012 - Springer
… ]F 2 as a fluorinating agent. The ex vivo … CFT to the monoamine transporters was studied
using in vivo blocking experiments with dopamine transporter [DAT], norepinephrine transporter

Progression in Parkinson's disease: A positron emission tomography study with a dopamine transporter ligand [18F]CFT

E Nurmi, HM Ruottinen, V Kaasinen… - Annals of Neurology …, 2000 - Wiley Online Library
… We studied the rate of progression of striatal dopamine transporter function in Parkinson's …
with [ 18 F]CFT positron emission tomography (PET). The PET scan was carried out twice at an …

Copper‐mediated nucleophilic radiofluorination of [18F]βCFT for positron emission tomography imaging of dopamine transporter

HM Yu, CY Li, SW Liu, CH Yang… - Journal of Labelled …, 2021 - Wiley Online Library
agent derived from 18 F 2 gas (Scheme 1). The difficulty of generating and handling 18 F 2
gas and the large amount of 19 F-β-CFT carrier … of [ 18 F]β-CFT using no-carrier-added [ 18 F]…

[18F]CFT ([18F]WIN 35,428), a radioligand to study the dopamine transporter with PET: Characterization in human subjects

A Laakso, J Bergman, M Haaparanta, H Vilkman… - Synapse, 1998 - Wiley Online Library
… We have characterized the usage of [18F]CFT (also known as [18F]WIN 35,428) as a
radioligand for in vivo studies of human dopamine transporter by PET. CFT was labeled with 18F to …

Striatal Distribution of Dopamine Transporters and Dopamine D2 Receptors at Different Stages of Parkinson's Disease: A CFT and RAC PET Study

M Mishina, K Ishii, M Suzuki… - The Neuroradiology …, 2011 - journals.sagepub.com
… tion of dopaminergic system in the striatum of the patients with PD at different stages using
CFT, … If the patients took antiparkinsonian agents, the administration of the agents was not …

Ex vivo and in vivo Evaluation of [18F]PR04.MZ in Rodents: A Selective Dopamine Transporter Imaging Agent

PJ Riss, F Debus, R Hummerich… - ChemMedChem …, 2009 - Wiley Online Library
… DAT inhibitor β-CFT (WIN 35,428). These results exemplify the good dopamine transporter
… suggests improved kinetic behaviour compared to FP-β-CIT, for example. This hypothesis is …