… of dopamine transporter ligands, such as [ 18 F]β-CFT, to … striatal uptake of dopamine
transporter ligand [ 123 I]β-CIT11 … reductions seen with [ 18 F]β-CFT. Differences in the severity of …

… on dopamine transporter ligand uptake during progression of PD. … dopamine transporter
function with PET during the progression of PD using [18F]CFT18,19 dopamine reuptake ligand. …

… in vivo density of monoamine transporters, including the dopamine transporter (DAT). [ 11
C]β-CFT is useful for studying DAT as a marker of dopaminergic innervation in animal models …

… of various dopamine transporter ligands to … of dopamine reuptake ligand[ 11 C]β-CFT
declines with age. This is in accordance with results obtained with other ligands, such as [ 123 I]β-…

… In conclusion, [18F]-CFT is a powerful ligand to demonstrate presynaptic dopaminergic defect
… CFT is more selective for dopamine transporter (compared to noradrenaline and serotonin …

… The regional distribution of [18F]CFT correlated well for known distribution of dopaminergic
… resembled that seen with other DAT ligands in vivo, including [11C]CFT. When the time-…

… as CFT or WIN 35,428) and the biodistribution of this compound in rats. 18F-labelled CFT
has … rats with a specific dopamine transport inhibitor, GBR 12909, showed that CFT binding is …

… ligand … ligand in the brain, and specifically bound ligand in the brain.Data were analyzed
based on this three-compartment, four-parameter model, fitting for blood– brain barrier transport …

… In the present study, [18F]-CFT-FE was synthesized and its potential as a PET ligand for
the quantitative imaging of DAT activity was evaluated in conscious rhesus monkeys. …

… DAT ligands based upon the substrates DA, AMP and β-… substrate-like dopamine transporter
(DAT) ligands investigated in … analogue β-CFT with respect to mutation. That is, the bivalent …