… disulfide bond. Proteolysis and peptide mass mapping revealed that Defr1 Y5C monomers
have β-defensin disulfide bond … and four intramolecular disulfide bonds, but because we were …

… disulfide bonds on the antimicrobial activity of defensins. The disulfide bonds are important
for holding the defensins in … from α defensins, the three disulfide linkages in β defensins are …

… disulfide pattern predicted for β-defensins resulted in significantly different products. While a
major product with the desired disulfide bonds … to a mixture of fully disulfide-bonded isomers …

… The observed d NN connectivities suggests that type I or type I′β-turns … the β-hairpin region
is a structure that is well conserved in all α- and β-defensins, peptides corresponding to the β…

… Because β-defensins contain three intramolecular disulphide-bridges 13 we investigated
the … , without the existence of intermediate states containing one or two disulphide-bridges. …

… of disulfide bridges or how they were connected. Our results suggest that a rigid β-sheet
structure or the presence of three disulfide … requirements for antibacterial activity in β-defensins. …

… into α, β and θ defensins on the basis of disulfide connectivity. Human β-defensins (HBDs) …
Disulfide connectivities in β-defensins are between cysteines 1, 5; 2, 4 and 3, 6 [13], [31], [36…

… separate antimicrobial and chemotactic activities of β-defensins to be dissected for the
first … action of β-defensins and may have important implications for the design of defensin-based …

… oxidize to form three intramolecular disulphide (S–S) bonds. The human and mouse defensins
have been … This article will concentrate on the β-defensin subclass. They are produced as …

… β-defensins consist of three β-strands arranged in an antiparallel sheet and held together
by three intramolecular disulfide bonds… with the canonical β-defensin disulfides. Since both …