Defensins in the immunology of bacterial infections

A Menendez, BB Finlay - Current opinion in immunology, 2007 - Elsevier
… , expanding the repertoire of the antimicrobial functions of defensins. It has been shown that
bacterial proteins can inactivate the action of defensins, and that pathogen type III secretion …

Understanding the roles of gingival beta-defensins

UK Gursoy, E Könönen - Journal of oral microbiology, 2012 - Taylor & Francis
bacterial membrane-selective characteristic of β-defensins … of β-defensins and negatively
charged bacterial membranes. … literature on pathogenic bacteria that induce β-defensins from …

Bacterial expression and antibiotic activities of recombinant variants of human β-defensins on pathogenic bacteria and M. tuberculosis

…, J Castañeda-Delgado, B Rivas-Santiago… - Protein expression and …, 2013 - Elsevier
Five variants of human β-defensins (HBDs) were expressed in Escherichia coli using two
vector systems (pET28a(+) and pQE30) with inducible expression by IPTG. The last vector has …

Applications of β-defensins against infectious pathogenic microorganisms

X Li, X Wang, J Du, X Bu, C Peng… - Expert Review of Anti …, 2024 - Taylor & Francis
… This review summarizes the activities of β-defensins against a variety of microbial pathogens
and their mechanisms of action, which include the destruction of bacterial biofilm structure …

Betadefensins: what are they REALLY doing in the oral cavity?

G Diamond, LK Ryan - Oral diseases, 2011 - Wiley Online Library
bacterial homeostasis and response to pathogens. This model is complicated, however,
by numerous other observations of β-defensin … periodontal pathogens to the different β-defensins

Mechanisms of disease: defensins in gastrointestinal diseases

J Wehkamp, K Fellermann, KR Herrlinger… - Nature clinical practice …, 2005 - nature.com
pathogenic bacteria or predisposing disease states. The constitutive production of defensins
in … A model for the role of defensins and intestinal bacteria in the pathogenesis and disease …

Antimicrobial activities of chicken β-defensin (4 and 10) peptides against pathogenic bacteria and fungi

HA Yacoub, AM Elazzazy, OAH Abuzinadah… - Frontiers in Cellular …, 2015 - frontiersin.org
… antimicrobial activities of β-defensin peptide-4 (sAvBD-4) and 10 (sAvBD-4) derived from
chickens against pathogenic organisms including bacteria and fungi. Ten bacterial strains and …

Porcine β-defensin 2 displays broad antimicrobial activity against pathogenic intestinal bacteria

EJA Veldhuizen, M Rijnders, EA Claassen… - Molecular …, 2008 - Elsevier
Defensins are small antimicrobial peptides that play an … , a recently discovered new porcine
defensin that is produced in … against a broad range of pathogenic bacteria, while it only …

The role of defensins in HIV pathogenesis

…, AA Lackner, E Porter, B Pahar - Mediators of …, 2017 - Wiley Online Library
… The HNP1–4 defensins affect a wide range of responses to infections with pathogenic
microbes. Among these, inhibition of HIV-1 infection was shown to be mediated by blocking viral …

Human beta-defensin-2

JM Schröder, J Harder - The international journal of biochemistry & cell …, 1999 - Elsevier
bacteria by a number of defensins, including HBD-1 and HBD-2 ([15], [12] and our unpublished
results). Why antimicrobial activity of β-defensins … eliminate pathogenic bacteria from the …