… β-isoform of the glucocorticoid receptor. Methods: We have measured expression of the α-
and β-glucocorticoid receptor isoforms in … who are glucocorticoid sensitive and resistant after 9 …

… dominant negative beta isoform of the glucocorticoid receptor thwarting the … isoform of the
human glucocorticoid receptor has also been seen in disease states resistant to glucocorticoid …

… glucocorticoids are mediated by a ubiquitous intracellular receptor protein, the glucocorticoid
receptor (GR), which functions as a hormone-activated transcription factor of glucocorticoid …

… hGRα and hGRβ are two isoforms of the human glucocorticoid receptor, which differ in the
structural composition of the carboxy-terminal end of the ligand-binding domain and therefore …

… natural and synthetic glucocorticoids to act on a target tissue and elicit specific biological
responses is dependent on the presence of the α isoform of the glucocorticoid receptor (GRα). …

… isoform that distinguishes it from hGRα. We demonstrate that hGRβ does not bind glucocorticoids
or … of hGRα is transcriptionally inactive on a glucocorticoid-responsive enhancer. It was …

… of glucocorticoid receptor isoforms from one gene. The potential role of glucocorticoid receptor
isoforms in … The proximal and distal regions of exon 9 are denoted α and β, respectively. …

… It has been suggested that this receptor isoform is involved in the induction of glucocorticoid
… the glucocorticoid receptor (GR), a steroid receptor that is a member of the nuclear receptor …

… contain exons 1-8 with different version of exon 9, exon 9α and -β, respectively. The two …
Gerdes and colleagues reported preliminary results showing a possible role for the γ-isoform in …

… regulating target cell responsiveness to glucocorticoids. High levels of hGRβ would confer
glucocorticoid resistance and low levels of hGRβ would confer glucocorticoid hypersensitivity. …