The latest advances in β-lactam/β-lactamase inhibitor combinations for the treatment of Gram-negative bacterial infections
KM Papp-Wallace - Expert opinion on pharmacotherapy, 2019 - Taylor & Francis
… The acquisition of β-lactamases, … infections. During the past decade, significant advances
were made in the development of novel BL-β-lactamase inhibitor (BLI) combinations to target β-…
were made in the development of novel BL-β-lactamase inhibitor (BLI) combinations to target β-…
β-lactam antibiotics: An overview from a medicinal chemistry perspective
LM Lima, BNM da Silva, G Barbosa… - European journal of …, 2020 - Elsevier
… Since then, several other β-lactam antibiotics have been introduced in the therapy, … bacterial
infections. Their antibacterial efficacy has been kept in check by the emergence of bacterial …
infections. Their antibacterial efficacy has been kept in check by the emergence of bacterial …
Drug delivery approaches to overcome bacterial resistance to β-lactam antibiotics
SC Abeylath, E Turos - Expert opinion on drug delivery, 2008 - Taylor & Francis
… that the β-lactams will soon no longer be able to stop deadly bacterial infections. Objective:
… a means to enhance the performance of β-lactam antibiotics against drug-resistant bacteria, …
… a means to enhance the performance of β-lactam antibiotics against drug-resistant bacteria, …
New β-lactam antibiotics and β-lactamase inhibitors
K Bush, MJ Macielag - Expert opinion on therapeutic patents, 2010 - Taylor & Francis
… , the β-lactams have become some of the most critical and widely-prescribed agents to
counteract bacterial infections … In this review, we provide descriptions of the newest β-lactams that …
counteract bacterial infections … In this review, we provide descriptions of the newest β-lactams that …
Linezolid versus glycopeptide or β-lactam for treatment of Gram-positive bacterial infections: meta-analysis of randomised controlled trials
… for the treatment of patients with infections caused by Gram-… or β-lactams for the treatment
of Gram-positive infections. 12 … more effective than glycopeptides or β-lactams (odds ratio [OR…
of Gram-positive infections. 12 … more effective than glycopeptides or β-lactams (odds ratio [OR…
Treatment of Bacterial Infections with β-Lactams: Cooperation with Innate Immunity
M Mondemé, C Carnoy, JC Sirard… - Infection and …, 2023 - Am Soc Microbiol
… the data that shed light on how β-lactams interact with myeloid cells during bacterial …
overview of the impact of β-lactams on innate immunity during the treatment of bacterial infections. …
overview of the impact of β-lactams on innate immunity during the treatment of bacterial infections. …
β-Lactam antibiotics renaissance
W Qin, M Panunzio, S Biondi - Antibiotics, 2014 - mdpi.com
… bacterial infections in both community and hospital settings. In particular, two types of strains
have compromised the clinical utility of currently available antibiotics and underscored the …
have compromised the clinical utility of currently available antibiotics and underscored the …
Beta‐lactam antibiotics: from antibiosis to resistance and bacteriology
KOKFAI KONG, L Schneper, K Mathee - Apmis, 2010 - Wiley Online Library
… more effective therapeutics to combat bacterial infection and has provided new research …
The concept of using chemicals to alleviate diseases, particularly infectious diseases, dates …
The concept of using chemicals to alleviate diseases, particularly infectious diseases, dates …
How β-lactam antibiotics enter bacteria: a dialogue with the porins
CE James, KR Mahendran, A Molitor, JM Bolla… - PloS one, 2009 - journals.plos.org
… This aspect of membrane physiology is a key issue in the field of infectious … infectious
diseases that are resistant to multiple antibiotics. Multi-drug resistant (MDR) bacterial infections …
diseases that are resistant to multiple antibiotics. Multi-drug resistant (MDR) bacterial infections …
Clinical role of β-lactam/β-lactamase inhibitor combinations
N Lee, KY Yuen, CR Kumana - Drugs, 2003 - Springer
… patients liable to Gram-positive bacterial infections, particularly those due to viridans … β-lactam/β-lactamase
inhibitor combinations hold out promise for preventing nosocomial infections …
inhibitor combinations hold out promise for preventing nosocomial infections …
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