A systematic review on clinical benefits of continuous administration of β-lactam antibiotics

JA Roberts, S Webb, D Paterson, KM Ho… - Critical care …, 2009 - journals.lww.com
β-lactams have been published since this meta-analysis ( 20–26 ). In this study, we systematically
reviewed … benefits of continuous infusion of β-lactam antibiotics exist and to appraise …

β lactam monotherapy versus β lactam-aminoglycoside combination therapy for sepsis in immunocompetent patients: systematic review and meta-analysis of …

M Paul, I Benuri-Silbiger, K Soares-Weiser, L Leibovici - Bmj, 2004 - bmj.com
… In this systematic review of all randomised trials we have shown that β lactam-aminoglycoside
combination therapy and β lactam monotherapy for the treatment of sepsis have similar …

β lactam monotherapy versus β lactam-aminoglycoside combination therapy for fever with neutropenia: systematic review and meta-analysis

M Paul, K Soares-Weiser, L Leibovici - Bmj, 2003 - bmj.com
… We performed a systematic review and meta-analysis of β lactam monotherapy and β lactam
that compared treatment with any β lactam alone with any combination of a β lactam and an …

Forty years of beta-lactam research.

GN Rolinson - The Journal of antimicrobial chemotherapy, 1998 - academic.oup.com
For more than 40 years the author has been involved in research in the field of beta-lactam
antibiotics. Much of this work was concerned with the development of the semisynthetic …

β-Lactam/β-lactamase inhibitors versus carbapenems for the treatment of sepsis: systematic review and meta-analysis of randomized controlled trials

S Shiber, D Yahav, T Avni, L Leibovici… - Journal of Antimicrobial …, 2015 - academic.oup.com
… We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs)
that compared BL/BLIs versus carbapenems for the treatment of sepsis. We attempted to …

New β-lactamβ-lactamase inhibitor combinations

D Yahav, CG Giske, A Grāmatniece… - … microbiology reviews, 2020 - Am Soc Microbiol
… of several novel β-lactamβ-lactamase inhibitor combinations (BLBLIs). In this review, we …
for treating Enterobacterales producing extended-spectrum β-lactamase (ESBL), Klebsiella …

Antibiotics in critically ill patients: a systematic review of the pharmacokinetics of β-lactams

J Gonçalves-Pereira, P Póvoa - Critical Care, 2011 - Springer
… Furthermore, β-lactam antibiotic PK are rarely analysed outside clinical trials. Therefore,
we performed a systematic review of studies that addressed the PK parameters of β-lactam

Recent developments in the field of βlactam antibiotics

W Dürckheimer, J Blumbach, R Lattrell… - … Edition in English, 1985 - Wiley Online Library
… This review attempts to summarize the chemistry and biological activity of the a-lactam
of detailed monographs and reviews on the extremely extensive field of p-lactam antibiotics, …

Diagnosis of nonimmediate reactions to βlactam antibiotics

A Romano, M Blanca, MJ Torres, A Bircher, W Aberer… - Allergy, 2004 - Wiley Online Library
… Drug Allergy (ENDA), in this review we describe the general guidelines for evaluating subjects
with nonimmediate reactions to β-lactams. β-Lactams, particularly penicillins, may cause …

β-lactam/β-lactamase inhibitor combinations: from then to now

KA Toussaint, JC Gallagher - Annals of Pharmacotherapy, 2015 - journals.sagepub.com
… resistance to β-lactams is through the production of β-lactamase enzymes. … to β-lactam
antibiotics is through the production of β-lactamase enzymes. These enzymes deactivate β-lactam