Piperacillintazobactam: a β-lactam/β-lactamase inhibitor combination

A Gin, L Dilay, JA Karlowsky, A Walkty… - Expert review of anti …, 2007 - Taylor & Francis
Piperacillintazobactam is a β-lactam/β-lactamasePiperacillintazobactam retains its in
vitro activity against broad-spectrum β-lactamase-producing and some extended-spectrum β

Piperacillin/tazobactam: a new beta-lactam/beta-lactamase inhibitor combination

LL Schoonover, DJ Occhipinti… - Annals of …, 1995 - journals.sagepub.com
Tazobactam is active against a broad spectrum of plasmid and chromosomally mediated …
mediated beta-lactamase enzymes. Piperacillin/tazobactam's expanded activity appears …

Antibiotic policy and prescribing strategies for therapy of extended‐spectrum βlactamase‐producing Enterobacteriaceae: the role of piperacillintazobactam

LR Peterson - Clinical Microbiology and Infection, 2008 - Wiley Online Library
… to b-lactam–b-lactamase inhibitor combinations, including piperacillintazobactam, when …
Current literature supports the action of piperacillintazobactam against susceptible strains …

[HTML][HTML] Empiric Piperacillin-Tazobactam versus Carbapenems in the Treatment of Bacteraemia Due to Extended-Spectrum Beta-Lactamase-Producing …

TM Ng, WX Khong, PNA Harris, PP De, A Chow… - PloS one, 2016 - journals.plos.org
… could be attributed to the effects of empiric carbapenem and piperacillin-tazobactam. Our
results suggested that piperacillin-tazobactam can be as effective as a carbapenem in the …

Optimal Piperacillin-Tazobactam Dosing Strategies against Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae

H Abodakpi, KT Chang, S Gao… - Antimicrobial agents …, 2019 - Am Soc Microbiol
… of piperacillin-tazobactam against ESBL-producing Enterobacteriaceae. Given the variability
of clinical responses to piperacillin-tazobactam, … targets for β-lactam/β-lactamase inhibitor …

Point-counterpoint: piperacillin-tazobactam should be used to treat infections with extended-spectrum-beta-lactamase-positive organisms

AN Schuetz, S Reyes, PD Tamma - Journal of clinical …, 2018 - Am Soc Microbiol
… Carbapenem therapy is associated with improved survival compared with piperacillin-tazobactam
for patients with extended-spectrum β-lactamase bacteremia. Clin Infect Dis 60:1319–…

PiperacillinTazobactam: A New βLactamβLactamase Inhibitor Combination

KP Daniel, LC Krop - … The Journal of Human Pharmacology and …, 1996 - Wiley Online Library
Piperacillin-tazobactam is approved by the FDA for the treatment of moderate to severe
infections due to piperacillin-resistant, piperacillintazobactam-susceptible, P-lactamase-…

Inhibition of β-lactamases by tazobactam and in-vitro antibacterial activity of tazobactam combined with piperacillin

F Higashitani, A Hyodo, N Ishida… - Journal of …, 1990 - academic.oup.com
… , a new /Mactamase inhibitor, combined with piperacillin was … of tazobactam against various
known types of filactamase … Table II shows the combined effect of piperacillin tazobactam

Beyond piperacillin-tazobactam: cefepime and AAI101 as a potent β-lactamβ-lactamase inhibitor combination

KM Papp-Wallace, CR Bethel, J Caillon… - Antimicrobial agents …, 2019 - Am Soc Microbiol
… to piperacillin in the presence of either AAI101 or tazobactam. … all five isogenic class D
β-lactamase producers examined, … to piperacillin when partnered with either tazobactam or …

Cefepime, Piperacillin-Tazobactam, and the Inoculum Effect in Tests with Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae

KS Thomson, ES Moland - Antimicrobial agents and …, 2001 - Am Soc Microbiol
piperacillin-tazobactam against ESBL-producing strains by determining the activities of these
two agents and six other parenteral β-lactam … , often acquiring additional β-lactamases, the …