Protective effect of resveratrol against toxicity induced by the mycotoxin, zearalenone in a rat model

P Virk, NAR Al-Mukhaizeem, SHB Morebah… - Food and Chemical …, 2020 - Elsevier
… With this premise, the present study has been designed to assess the protective effect of
resveratrol on zearalenone induced genotoxicity and immunotoxicity in adult male Wistar rat. …

The neuroprotective effects of phytoestrogen α-zearalanol on β-amyloid-induced toxicity in differentiated PC-12 cells

Y Dong, N Yang, Y Liu, Q Li, P Zuo - European journal of pharmacology, 2011 - Elsevier
… To investigate the mechanisms involved in the protective effects of α-ZAL, the level of total
SOD, GSH-Px and MDA were measured by using a commercial assay kit. As shown in Table 1…

… Effects of the Hydroethanolic Extract of Fridericia chica on Undifferentiated Human Neuroblastoma Cells Exposed to α-Zearalenol (α-ZEL) and β-Zearalenol (β-ZEL)

N Alvarez-Ortega, K Caballero-Gallardo… - Toxins, 2021 - mdpi.com
… The aim of this research was to determine the protective effects of the hydroethanolic
extract from the F. chica leaves (HEFc) against the cytotoxicity of zearalenone (α-ZEL) and β-ZEL …

Protective effect of Crocin against zearalenone-induced oxidative stress in liver and kidney of Balb/c mice

I Ben Salem, M Boussabbeh, S Helali… - … Science and Pollution …, 2015 - Springer
… In the present study, we aimed to evaluate the protective effect of Crocin (CRO), a natural …
two metabolites, α- and β-zearalenol. α-Zearalenol is the major metabolite in humans, and it …

Protective effect of aqueous extract of Allium sativum against zearalenone toxicity mediated by oxidative stress

S Abid-Essefi, C Zaied, C Bouaziz, IB Salem… - Experimental and …, 2012 - Elsevier
… The aim of the current study was to evaluate the protective effects of aqueous extract of
Allium sativum (AEA), against ZEN-induced cytotoxicity, reactive oxygen species (ROS) …

Biomarkers of exposure to zearalenone in in vivo and in vitro studies

P Llorens, M Herrera, A Juan-García, JJ Payá, JC Moltó… - Toxins, 2022 - mdpi.com
… It has highlighted the importance of determining α-zearalenol and β-zearalenol biomarkers
to estimate the probable dietary intake (PDI) of a specific population or to characterize the …

Activation of ER stress and apoptosis by α-and β-zearalenol in HCT116 cells, protective role of Quercetin

IB Salem, A Prola, M Boussabbeh, A Guilbert, H Bacha… - Neurotoxicology, 2016 - Elsevier
… We also evaluated the protective effect of Quercetin (QUER) against α- and β-ZOL-induced …
and β-ZOL-induced ER stress To evaluate the protective effect of QUER against α-ZOL- and β

Comparative study of toxic effects of zearalenone and its two major metabolites α‐zearalenol and βzearalenol on cultured human Caco‐2 cells

S Abid‐Essefi, C Bouaziz… - … of Biochemical and …, 2009 - Wiley Online Library
… ABSTRACT: Zearalenone (ZEN) is a fusarotoxin converted predominantly into α-zearalenol
(α-Zol) and β-zearalenol (β-Zol) by hepatic hydroxysteroid dehydrogenases. The feeding of …

Protective effect of proanthocyanidin on mice Sertoli cell apoptosis induced by zearalenone via the Nrf2/ARE signalling pathway

M Long, SH Yang, W Shi, P Li, Y Guo, J Guo… - … Science and Pollution …, 2017 - Springer
… This study evaluated the protective effect of proanthocyanidin (PC) on the cytotoxicity of the
… These results demonstrated that PC conferred protective effects against oxidative damage …

Cytotoxicity effects induced by Zearalenone metabolites, α Zearalenol and β Zearalenol, on cultured Vero cells

ZOB Othmen, E El Golli, S Abid-Essefi, H Bacha - Toxicology, 2008 - Elsevier
… in various species are α and β Zearalenol. In vivo, Zen is mainly … β Zearalenol in cultured
cells. For this purpose, the MTT assay was carried out and the influence of α and β Zearalenol