Involvement of the MKK6-p38γ cascade in γ-radiation-induced cell cycle arrest

X Wang, CH McGowan, M Zhao, L He… - … and cellular biology, 2000 - Taylor & Francis
cell death is considered to be the mechanism for cancer cell … of the p38 pathway in γ-irradiated
cells. The function of these … all p38 isoforms are activated by γ irradiation, that the active …

A system for mutation measurement in mammalian cells: Application to γ-irradiation

TT Puck, R Johnson… - Proceedings of the …, 1997 - National Acad Sciences
… all (or almost all) lesions contributing to cell death under these specific experimental conditions.
… that are not repaired or do not contribute to cell death which are not affected by caffeine. …

Parp-2 is required to maintain hematopoiesis following sublethal γ-irradiation in mice

J Farrés, J Martín-Caballero, C Martínez… - Blood, The Journal …, 2013 - ashpublications.org
… of cell death were … Cell death after γ-irradiation correlated with an impaired capacity to
repair DNA damage in the absence of Parp-2. Upon exposure to sublethal doses of γ-irradiation, …

Protein expression following γ-irradiation relevant to growth arrest and apoptosis in colon cancer cells

D Pfeifer, Å Wallin, B Holmlund, XF Sun - Journal of cancer research and …, 2009 - Springer
… It is possible though that the KM12C cell line was eliminated through other cell death
pathways, such as necrosis and mitotic catastrophe, not studied in this paper. Although all three …

Protein kinase C-η regulates resistance to UV-and γ-irradiation-induced apoptosis in glioblastoma cells by preventing caspase-9 activation

IM Hussaini, JE Carpenter, GT Redpath… - Neuro …, 2002 - academic.oup.com
… -h in preventing UVand g-irradiation–induced apoptosis and in caspasedependent signaling
pathways that mediate cell death. Exposure to UV or g irradiation killed 80% to 100% of …

NF-κB is required for smac mimetic-mediated sensitization of glioblastoma cells for γ-irradiation–induced apoptosis

R Berger, C Jennewein, V Marschall, S Karl… - Molecular cancer …, 2011 - AACR
… –induced apoptosis because Enbrel, a TNFα blocking antibody, did not prevent cell death
induction. TNFα has previously been implicated to mediate cell death induced by single agent …

[HTML][HTML] In situ vaccination caused by diverse irradiation-driven cell death programs

Y Wang, Y Li, Y Yang, M Swift, Z Zhang, S Wu… - Theranostics, 2024 - ncbi.nlm.nih.gov
… the modes of cell death programs driven by irradiation and their … of multiple cell death
programs initiated by irradiation, and … In addition, irradiation-induced interferon-γ (IFN-γ) has been …

Irradiation induces G2/M cell cycle arrest and apoptosis in p53-deficient lymphoblastic leukemia cells without affecting Bcl-2 and Bax expression

E Strasser-Wozak, BL Hartmann, S Geley… - Cell Death & …, 1998 - nature.com
… Gamma irradiation induces DNA damage which is a known … The concept that irradiation
causes cell death through p53… sensitivity to irradiation-induced cell death in various cell types (…

Inhibition of c-Jun N-terminal kinase activity enhances vestibular schwannoma cell sensitivity to gamma irradiation

WY Yue, JJ Clark, M Telisak, MR Hansen - Neurosurgery, 2013 - journals.lww.com
… 2A phosphorylation (γ-H2AX) after gamma irradiation (IR) in vestibular schwannoma (VS) …
Here, our study focused on apoptotic cell death; given the limited number of primary VS cells

Extreme sensitivity of some intestinal crypt cells to X and γ irradiation

CS Potten - Nature, 1977 - nature.com
… hypersensitive cells at the base of the crypts can be dcmonstrated after whole-body X or y
irradiation, and to describe the time sequence for the production and loss of these killed cells