… of NLRP3 inflammasome by Platycodin D via the TLR4/MyD88/NF-κB pathway contributes to attenuation of lipopolysaccharide induced acute lung injury in rats

Y Wu, D Huang, X Wang, C Pei, W Xiao, F Wang… - International …, 2021 - Elsevier
lung tissue. In addition, PLD suppressed the activation of NLRP3 inflammatory microsomes
and the NF-κB … against LPS-induced ALI by inhibiting NLRP3 and NF-κB signaling pathway. …

Ozone exposure promotes pyroptosis in rat lungs via the TLR2/4-NF-κB-NLRP3 signaling pathway

L Tian, J Yan, K Li, W Zhang, B Lin, W Lai, L Bian, H Liu… - Toxicology, 2021 - Elsevier
… N-GSDMD, caspase-1, and NLRP3 protein expression in rat lung tissue increased, and IL-1β
in alveolar lavage fluid, serum, and lung tissue. The content of inflammatory factors, IL-6, IL-…

Sepsis-induced acute lung injury in young rats is relieved by calycosin through inactivating the HMGB1/MyD88/NF-κB pathway and NLRP3 inflammasome

G Chen, Y Hou, X Li, R Pan, D Zhao - International immunopharmacology, 2021 - Elsevier
… -κB, NF-κB and NLRP3 protein levels in rat lung tissues … NLRP3 in the lung tissues. NSP >
0.05 (vs. Sham group); DG. HMGB1, MyD88, NF-κB and NLRP3 mRNA expressions in rat lung

Procyanidin B2 protects rats from paraquat-induced acute lung injury by inhibiting NLRP3 inflammasome activation

Y Jiang, W Yang, S Gui - Immunobiology, 2018 - Elsevier
… showed remarkably decreased NLRP3, ASC and caspase-1 signals in the lung tissues in a
… activation of NLRP3 inflammasome in the lung tissue induced by paraquat in the rat model. …

Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs

PM Peeters, IMJ Eurlings, TN Perkins… - Particle and fibre …, 2014 - Springer
… in rat lung tissue are affected over time when exposed to coated and uncoated crystalline
minerals. Representative lung tissue sections of rats … alveolar septa in lungs of rats exposed to …

Baicalin Ameliorates Lung Injury in Rats by Inhibiting NLRP3 Inflammasome Activation via NF-B Signaling Pathway

X Yang, J Han, Z Huan, C Xu, Q Wang… - The American Journal of …, 2023 - World Scientific
… of BA in pulmonary injury, we established the HS-induced rat models and detected
pathological alterations in the lung tissues of rats. As shown in Fig. 1A, after HS activation, the rats

Qingwenzhike Prescription Alleviates Acute Lung Injury Induced by LPS via Inhibiting TLR4/NF-kB Pathway and NLRP3 Inflammasome Activation

C Zhang, X Wang, C Wang, C He, Q Ma, J Li… - Frontiers in …, 2021 - frontiersin.org
rat model stimulated by LPS. The possible mechanisms of QWZK were supposed by inhibiting
TLR4/NF-κB pathway and NLRP3 … -induced pulmonary inflammation in rat lung tissues …

Influenza a virus triggers acute exacerbation of chronic obstructive pulmonary disease by increasing proinflammatory cytokines secretion via NLRP3 inflammasome …

S Ji, MY Dai, Y Huang, XC Ren, ML Jiang, JP Qiao… - Journal of …, 2022 - Springer
… of COPD rats, we examined the expression of NLRP3 inflammasome components in BALF
… a range of cell types induce potent NF-κB-dependent secondary cytokine about IAV induced …

Melatonin attenuates airway inflammation via SIRT1 dependent inhibition of NLRP3 inflammasome and IL-1β in rats with COPD

Z Peng, W Zhang, J Qiao, B He - International Immunopharmacology, 2018 - Elsevier
… inflammasome in COPD, we measured the protein expressions of NLRP3, cleaved caspase-1
and ASC in the lung tissues of various groups. As shown in Fig. 4, the protein expressions …

Effects of Nintedanib on the Lungs via NLRP3 in a Model of Lipopolysaccharide-induced Acute Lung Injury in Rats

G Tanriverdiyeva, P Aydin, E TOKTAY… - NAMIK KEMAL …, 2024 - avesis.atauni.edu.tr
… nintedanib lowered the elevated NLRP3, caspase-1, IL-1β, and NF-κB expressions and the
… of rats with LPS-induced ALI. The findings obtained for the rats included in the lung injury …