[HTML][HTML] Antibody resistance of SARS-CoV-2 variants B. 1.351 and B. 1.1. 7

P Wang, MS Nair, L Liu, S Iketani, Y Luo, Y Guo… - Nature, 2021 - nature.com
… Much of our findings on B.1.351 would probably be similar for this emergent variant. N501Y
… to treat or prevent SARS-CoV-2. Both B.1.1.7 and B.1.351 are resistant to neutralization by …

Sensitivity of infectious SARS-CoV-2 B. 1.1. 7 and B. 1.351 variants to neutralizing antibodies

D Planas, T Bruel, L Grzelak, F Guivel-Benhassine… - Nature medicine, 2021 - nature.com
1.351 strains from acutely infected individuals. We examined sensitivity of the two variants
to SARS-CoV… , in comparison with a D614G reference virus. We utilized a new rapid …

[HTML][HTML] SARS-CoV-2 variants B. 1.351 and P. 1 escape from neutralizing antibodies

M Hoffmann, P Arora, R Groß, A Seidel, BF Hörnich… - Cell, 2021 - cell.com
… Here, we show that the S protein of the B.1.1.7, B.1.351, and P.1 variants mediate robust … S
proteins of the B.1.351 and P.1 variants. Similarly, these variants were less efficiently inhibited …

[HTML][HTML] Detection of B. 1.351 SARS-CoV-2 variant strain—Zambia, december 2020

M Mwenda - MMWR. Morbidity and mortality weekly report, 2021 - cdc.gov
… the B.1.351 variant was introduced to Zambia. Because the B.1.351 variant has been detected
… for the B.1.351 variant as well as early detection of emerging variants that might affect the …

[HTML][HTML] SARS-CoV-2 B. 1.1. 7 and B. 1.351 spike variants bind human ACE2 with increased affinity

M Ramanathan, ID Ferguson, W Miao, PA Khavari - BioRxiv, 2021 - ncbi.nlm.nih.gov
… the ACE2 at nearly five-fold greater affinity than the original SARS-COV-2 RBD. We also
find that the B.1.1.7 variant, binds two-fold more tightly to ACE2 than the SARS-COV-2 RBD. …

Prevention and therapy of SARS-CoV-2 and the B. 1.351 variant in mice

DR Martinez, A Schäfer, SR Leist, D Li, K Gully… - Cell reports, 2021 - cell.com
… the B.1.351 variant of … SARS-CoV-2 infections and the continued clinical development of
the C144 and C135 antibody combination to treat patients infected with SARS-CoV-2 variants

[HTML][HTML] Infection-and vaccine-induced antibody binding and neutralization of the B. 1.351 SARS-CoV-2 variant

VV Edara, C Norwood, K Floyd, L Lai… - Cell host & …, 2021 - cell.com
… and the emerging B.1.351 variant containing additional spike … titers to the B.1.351 variant
receptor-binding domain of the … SARS-CoV-2 B.1.351 variant compared to the B.1 variant. …

Evidence of escape of SARS-CoV-2 variant B. 1.351 from natural and vaccine-induced sera

D Zhou, W Dejnirattisai, P Supasa, C Liu, AJ Mentzer… - Cell, 2021 - cell.com
… B.1.1.7 and B.1.351, is causing considerable concern. Here, we examine neutralization
of a B.1.351 viral isolate and compare this to neutralization of Victoria (SARS-CoV-2/human/AUS/…

[HTML][HTML] The SARS-CoV-2 B. 1.351 lineage (VOC β) is outgrowing the B. 1.1. 7 lineage (VOC α) in some French regions in April 2021

B Roquebert, S Trombert-Paolantoni… - …, 2021 - eurosurveillance.org
… Our results call for more detailed analyses regarding the link between the transmission
advantage of the B.1.351 variant and the proportion of the population with immunity (following …

Structure-function analyses of new SARS-CoV-2 variants B. 1.1. 7, B. 1.351 and B. 1.1. 28.1: clinical, diagnostic, therapeutic and public health implications

J Singh, J Samal, V Kumar, J Sharma, U Agrawal… - Viruses, 2021 - mdpi.com
… on implications of emerging SARS-CoV-2 variants based on … anti-viral candidates against
SARS-CoV-2, likely necessitating roll … reinfections with emerging variants can have significant …