3, 4‐Dimethoxychalcone induces autophagy through activation of the transcription factors TFE 3 and TFEB
… ATG5 −/− cells, which however continued to manifest the upregulation of p62 and LC3-I (Fig
EV2A–C, Appendix Fig S3A and B). The upregulation of p62 that could be observed after a …
EV2A–C, Appendix Fig S3A and B). The upregulation of p62 that could be observed after a …
Synthesis and Melanogenesis Effect of 7, 8-Dimethoxy-4-Methylcoumarin via MAPK Signaling-Mediated Microphthalmia-Associated Transcription Factor Upregulation
MS Kang, SC Jang, T Park, MS Kim… - Natural Product …, 2022 - journals.sagepub.com
… associated transcription factor (MITF) is a master regulator. One coumarin family member
7,8… Therefore, we first synthesized DHMC derivatives via methylation to obtain 7,8-dimethoxy-4-…
7,8… Therefore, we first synthesized DHMC derivatives via methylation to obtain 7,8-dimethoxy-4-…
Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3′, 4′-dimethoxy-α-naphthoflavone
IA Murray, CA Flaveny, CR Chiaro, AK Sharma… - Molecular …, 2011 - ASPET
We have characterized previously a class of aryl hydrocarbon receptor (AHR) ligand termed
selective AHR modulators (SAhRMs). SAhRMs exhibit anti-inflammatory properties, …
selective AHR modulators (SAhRMs). SAhRMs exhibit anti-inflammatory properties, …
7, 8-Dimethoxycoumarin stimulates melanogenesis via MAPKs mediated MITF upregulation
N Lee, YC Chung, YB Kim, SM Park… - Die Pharmazie-An …, 2020 - ingentaconnect.com
… At transcription level, the expression of melanogenic enzymes is upregulated by the binding
of microphthalmia-associated transcription factor (MITF), which is involved in pigmentation, …
of microphthalmia-associated transcription factor (MITF), which is involved in pigmentation, …
Nuclear Factor E2–Related Factor 2–Mediated Induction of NAD (P) H: Quinone Oxidoreductase 1 by 3, 5-Dimethoxy-trans-stilbene
EJ Park, HY Min, HJ Park, HJ Chung, YH Ahn… - Journal of …, 2011 - Elsevier
… NQO1 induction activity through up-regulation of both protein … and leaves of the Pinus species
(8). Pinosylvin has anti-fungal, anti-… To examine the localization of transcription factors, cell …
(8). Pinosylvin has anti-fungal, anti-… To examine the localization of transcription factors, cell …
[HTML][HTML] The Hallucinogenic Serotonin2A Receptor Agonist, 2,5-Dimethoxy-4-Iodoamphetamine, Promotes cAMP Response Element Binding Protein-Dependent …
LA Desouza, M Benekareddy, SE Fanibunda… - Frontiers in Molecular …, 2021 - frontiersin.org
… the contribution of the transcription factor cyclic adenosine … leads to a rapid transcriptional
upregulation of several neuronal … We treated WT and CREBαδ KO mice with vehicle or DOI (8 …
upregulation of several neuronal … We treated WT and CREBαδ KO mice with vehicle or DOI (8 …
[HTML][HTML] Anti-inflammatory and antioxidant effects of 2, 7-dihydroxy-4, 6-dimethoxy phenanthrene isolated from Dioscorea batatas Decne
… are mediated by upregulation of nuclear factor kappa-light-… signaling protein MAPK and the
transcription factor NF-κB [9, 10], … Yield of eight compounds of chromatographic fraction #8. …
transcription factor NF-κB [9, 10], … Yield of eight compounds of chromatographic fraction #8. …
Methylated chrysin induces co-ordinated attenuation of the canonical Wnt and NF-kB signaling pathway and upregulates apoptotic gene expression in the early …
MS Khan, D Halagowder, SN Devaraj - Chemico-biological interactions, 2011 - Elsevier
… Recently, we reported that dimethoxy flavone (DMF), a … the first dose beginning at experimental
week 8 as in group B rats. … Mice lacking RelA subunit of Rel/NF-kB transcription factors in …
week 8 as in group B rats. … Mice lacking RelA subunit of Rel/NF-kB transcription factors in …
Anti-neuroinflammatory activity of 6, 7-dihydroxy-2, 4-dimethoxy phenanthrene isolated from Dioscorea batatas Decne partly through suppressing the p38 MAPK/NF …
… exposed to the CCK-8 reagent. The absorbance was … upregulation in HT22 cells by DHDMP
was assumed to be independent of Nrf2. The protein Nrf2 is an upstream transcription factor …
was assumed to be independent of Nrf2. The protein Nrf2 is an upstream transcription factor …
[HTML][HTML] The compound 2‑benzylthio‑5, 8‑dimethoxynaphthalene‑1, 4‑dione leads to apoptotic cell death by increasing the cellular reactive oxygen species levels in …
GN Shen, J Li, YH Jin, HN Sun… - Experimental and …, 2020 - spandidos-publications.com
… ‑apoptotic anticancer potential of several 5,8‑dimethoxy‑1,4‑… levels (Bad upregulation and
Bcl-2 downregulation), which led to … , such as ERK upregulation and AKT downregulation (55). …
Bcl-2 downregulation), which led to … , such as ERK upregulation and AKT downregulation (55). …
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