In this article, a highly reliable radiation-hardened-by-design (RHBD) 10T static random access memory (SRAM) cell is proposed. In space, the impact of alpha particles and cosmic radiation flips the node data resulting in loss of data in conventional 6T SRAM. The proposed SRAM has quad-nodes, which stores the data. The architecture is designed with a quad-latch topology and simulated in 65-nm CMOS technology with a supply voltage of 1.2 V. The result shows that the design can tolerate both 0 to 1 and 1 to 0 single event upset errors on any one of its nodes. The read and write access times of the proposed design are 88.78 and 241.77 ps, respectively. The static noise margin for read, write, and hold operations are 379.01, 906.51, and 637.1 mV, respectively. The proposed architecture takes an area of 6.52 μm.