过去一年中添加的文章,按日期排序

Investigations into the Treatment of Organophosphorus Exposed Acetylcholinesterase Variants by Quinone Methide Precursors.

AK Buck - 2024 - rave.ohiolink.edu
2 天前 - … using oximes aim to reactivate OP-inhibited AChE but are … Resurrection kinetic
studies show that efficacy of QMPs … as rapid inhibition rates by OP compounds, slower aging

… Methide Precursors: Effective and Broad-Scope Nonoxime Reactivators of Organophosphorus-Inhibited Cholinesterases and Resurrectors of Organophosphorus …

AR Lovins, KA Miller, AK Buck, DS Ensey… - ACS Chemical …, 2024 - ACS Publications
158 天前 - … Furthermore, an in vitro kinetic analysis show that 10c has … can result from the
aging of this inhibited OP structure. O-… to reactivate AChE inhibited with organophosphate

… of the covalent methanesulfonyl fluoride acetylcholinesterase adduct: Insights into an aged‐like inactive complex susceptible to reactivation by a combination of …

J Stojan, A Pesaresi, A Meden, D Lamba - Protein Science, 2024 - Wiley Online Library
165 天前 - … , known as organophosphorus compounds inactivate … by reversible quaternary
ammonium inhibitors (Kitz & Wilson, … a comprehensive multistep kinetic study to characterize …

[HTML][HTML] Inhibition with simultaneous spontaneous reactivation and aging of acetylcholinesterase by organophosphorus compounds: Demeton-S-methyl as a model

J Estévez, L Pizarro, J Marsillach, C Furlong… - Chemico-Biological …, 2024 - Elsevier
322 天前 - … where inhibition, spontaneous reactivation and aging reaction … or with or without
chemical hydrolysis of the inhibitor [7,8]. … kinetic model of simultaneous inhibition, spontaneous …