Extracellular signals are the key components of microbial cell–cell communication systems.
This report identified a diffusible signal factor (DSF), which regulates virulence in
Xanthomonas campestris pv. campestris, as cis‐11‐methyl‐2‐dodecenoic acid, an α, β
unsaturated fatty acid. Analysis of DSF derivatives established the double bond at the α, β
positions as the most important structural feature for DSF biological activity. A range of
bacterial pathogens, including several Mycobacterium species, also displayed DSF‐like …

Extracellular signals are the key components of microbial cell-cell communication systems.
This report identified a diffusible signal factor (DSF), which regulates virulence in
Xanthomonas campestris pv. campestris, as cis-11-methyl-2-dodecenoic acid, an α, β
unsaturated fatty acid. Analysis of DSF derivatives established the double bond at the α, β
positions as the most important structural feature for DSF biological activity. A range of
bacterial pathogens, including several Mycobacterium species, also displayed DSF-like …