Afatinib and Erlotinib in the treatment of squamous-cell lung cancer

M Tagliamento, C Genova, E Rijavec… - Expert Opinion on …, 2018 - Taylor & Francis
erlotinib and afatinib in SCC of the lung. The authors explore the rationale of targeting EGFR
in SCC and the pharmacological properties of erlotinib … 8 trial, which compared erlotinib and …

Development and in vitro evaluation of core–shell type lipid–polymer hybrid nanoparticles for the delivery of erlotinib in non-small cell lung cancer

B Mandal, NK Mittal, P Balabathula, LA Thoma… - European journal of …, 2016 - Elsevier
erlotinib loaded CSLPHNPs compared to erlotinib solution in A549 cells. Therefore, CSLPHNPs
could be a potential delivery system for erlotiniberlotinib loaded CSLPHNPs (erlotinib

Noninvasive Detection of EGFR T790M in Gefitinib or Erlotinib Resistant Non–Small Cell Lung Cancer

Y Kuang, A Rogers, BY Yeap, L Wang… - Clinical Cancer …, 2009 - AACR
… In this study we examined the ability to detect EGFR T790M from plasma DNA from
NSCLC patients that had clinically developed acquired resistance to gefitinib or erlotinib. We …

Development of erlotinib-loaded nanotransferosomal gel for the topical treatment of ductal carcinoma in situ

B Mangla, P Mittal, P Kumar, S Javed, W Ahsan… - …, 2024 - Future Medicine
… Aims: This study was aimed to formulate erlotinib (ERL)-loaded transferosomal gel (ERL@TG)
intended for topical application for the treatment of ductal carcinoma in situ. Materials & …

Synergistic effect between erlotinib and MEK inhibitors in KRAS wild-type human pancreatic cancer cells

CH Diep, RM Munoz, A Choudhary, DD Von Hoff… - Clinical cancer …, 2011 - AACR
… the synergistic effect between erlotinib and MAP kinase kinase (MEK) inhibitors in pancreatic
cancer cells and animal models. We show that the combination of erlotinib, an epidermal …

Bevacizumab and erlotinib: a promising new approach to the treatment of advanced NSCLC

RS Herbst, A Sandler - The Oncologist, 2008 - academic.oup.com
… Although a direct comparison of erlotinib efficacy with that of docetaxel and pemetrexed
will be possible only when data are available from comparative trials, the efficacy of erlotinib

Comparison of epidermal growth factor receptor tyrosine kinase inhibitors for patients with lung adenocarcinoma harboring different epidermal growth factor receptor …

S Park, SY Lee, D Kim, YS Sim, JS Ryu, J Choi, SH Lee… - BMC cancer, 2021 - Springer
… We investigated the clinical outcomes of afatinib, erlotinib, and gefitinib according to EGFR
… is uncertain, as comparative studies have been scarce. The present study demonstrated that …

[HTML][HTML] Repurposing sertraline sensitizes non–small cell lung cancer cells to erlotinib by inducing autophagy

X Jiang, W Lu, X Shen, Q Wang, J Lv, M Liu, F Cheng… - JCI insight, 2018 - ncbi.nlm.nih.gov
… cells and shows a synergy with erlotinib. Specifically, the cotreatment of sertraline and …
In this study, we demonstrated that sertraline enhanced the therapeutic efficacy of erlotinib in …

EGFR Mutant Structural Database: computationally predicted 3D structures and the corresponding binding free energies with gefitinib and erlotinib

L Ma, DD Wang, Y Huang, H Yan, MP Wong… - BMC …, 2015 - Springer
study, we created an EGFR Mutant Structural Database, containing over one hundred EGFR
mutants and their binding free energies with reversible TKIs gefitinib and erlotinib. … erlotinib. …

A systematic review of pharmacoeconomic evaluations of erlotinib in the first-line treatment of advanced non-small cell lung cancer

CTT Nguyen, F Petrelli, S Scuri, BT Nguyen… - The European Journal of …, 2019 - Springer
… After converting the currencies used in the studies to I$, using the CPI and PPP, we found
that erlotinib in the first-line treatment of advanced NSCLC had incremental cost-effectiveness …