During the past decade, mass spectrometry imaging (MSI) has become a robust and
versatile methodology to support modern pharmaceutical research and development. The
technologies provide data on the biodistribution, metabolism, and delivery of drugs in
tissues, while also providing molecular maps of endogenous metabolites, lipids, and
proteins. This allows researchers to make both pharmacokinetic and pharmacodynamic
measurements at cellular resolution in tissue sections or clinical biopsies. Despite drug …