Insect neurohormones (biogenic amines, neuropeptides, and protein hormones) and their G
protein-coupled receptors (GPCRs) play a central role in the control of behavior,
reproduction, development, feeding and many other physiological processes. The recent
completion of several insect genome projects has enabled us to obtain a complete inventory
of neurohormone GPCRs in these insects and, by a comparative genomics approach, to
analyze the evolution of these proteins. The red flour beetle Tribolium castaneum is the …