A metal-free tandem C–C/C–O bond formation approach to diversely functionalized tetrasubstituted furans
C Raji Reddy, M Damoder Reddy - The Journal of Organic …, 2014 - ACS Publications
C Raji Reddy, M Damoder Reddy
The Journal of Organic Chemistry, 2014•ACS PublicationsA novel and efficient method for the synthesis of diversely functionalized furans is developed
via DBU-mediated tandem Michael addition/5-exo-dig-cycloisomerization of enynes and
keto-methylenes. This [3+ 2]-annulation is operationally simple under metal-free reaction
conditions with 100% atom economy and broad substrate scope.
via DBU-mediated tandem Michael addition/5-exo-dig-cycloisomerization of enynes and
keto-methylenes. This [3+ 2]-annulation is operationally simple under metal-free reaction
conditions with 100% atom economy and broad substrate scope.
A novel and efficient method for the synthesis of diversely functionalized furans is developed via DBU-mediated tandem Michael addition/5-exo-dig-cycloisomerization of enynes and keto-methylenes. This [3 + 2]-annulation is operationally simple under metal-free reaction conditions with 100% atom economy and broad substrate scope.
ACS Publications
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