A methodology for the production of microfabricated electrospun membranes for the creation of new skin regeneration models
IO Asencio, S Mittar, C Sherborne… - Journal of Tissue …, 2018 - journals.sagepub.com
The continual renewal of the epidermis is thought to be related to the presence of
populations of epidermal stem cells residing in physically protected microenvironments (rete
ridges) directly influenced by the presence of mesenchymal fibroblasts. Current skin in vitro
models do acknowledge the influence of stromal fibroblasts in skin reorganisation but the
study of the effect of the rete ridge-microenvironment on epidermal renewal still remains a
rich topic for exploration. We suggest there is a need for the development of new in vitro …
populations of epidermal stem cells residing in physically protected microenvironments (rete
ridges) directly influenced by the presence of mesenchymal fibroblasts. Current skin in vitro
models do acknowledge the influence of stromal fibroblasts in skin reorganisation but the
study of the effect of the rete ridge-microenvironment on epidermal renewal still remains a
rich topic for exploration. We suggest there is a need for the development of new in vitro …
A methodology for the production of microfabricated electrospun membranes for the creation of new skin regeneration models
I Ortega Asencio, M Shweta Mittar… - Journal of Tissue …, 2018 - eprints.whiterose.ac.uk
The continual renewal of the epidermis is thought to be related to the presence of
populations of epidermal stem cells residing in physically protected microenvironments (rete
ridges) directly influenced by the presence of mesenchymal fibroblasts. Current skin in vitro
models do acknowledge the influence of stromal fibroblasts in skin reorganisation but the
study of the effect of the rete ridge-microenvironment on epidermal renewal still remains a
rich topic for exploration. We suggest there is a need for the development of new in vitro …
populations of epidermal stem cells residing in physically protected microenvironments (rete
ridges) directly influenced by the presence of mesenchymal fibroblasts. Current skin in vitro
models do acknowledge the influence of stromal fibroblasts in skin reorganisation but the
study of the effect of the rete ridge-microenvironment on epidermal renewal still remains a
rich topic for exploration. We suggest there is a need for the development of new in vitro …
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