过去一年中添加的文章，按日期排序
[HTML][HTML] The Leukemic Isocitrate Dehydrogenase (IDH) 1/2 Mutations Impair Myeloid and Erythroid Cell Differentiation of Primary Human Hematopoietic Stem and …
2 天前 - … is poorly understood and mainly explored in animal models. Here, we study
isocitrate dehydrogenase (IDH) gene mutations in the human model of HSPC and discuss the …
isocitrate dehydrogenase (IDH) gene mutations in the human model of HSPC and discuss the …
Bioactive nanocomposite hydrogel enhances postoperative immunotherapy and bone reconstruction for osteosarcoma treatment
X Chu, B Mi, Y Xiong, R Wang, T Liu, L Hu, C Yan… - Biomaterials, 2024 - Elsevier
2 天前 - … bone tumor models, we first subcutaneously injected a suspension of K7M2 cells (1.0
× 10 6 ) into the dorsal region of BALB/c mice, and the in vivo tumor models … animal model. …
× 10 6 ) into the dorsal region of BALB/c mice, and the in vivo tumor models … animal model. …
Curcumin Alleviates Osteoarthritis Through the p38MAPK Pathway: Network Pharmacological Prediction and Experimental Confirmation
X Wang, H Yu, Y Zhang, X Chang, C Liu… - Journal of …, 2024 - Taylor & Francis
3 天前 - … animal models and ultimately clinical trials should be conducted to validate its
safety and efficacy and to determine the optimal dosage, route of administration, and treatment …
safety and efficacy and to determine the optimal dosage, route of administration, and treatment …
[HTML][HTML] Based on NF-κB and Notch1/Hes1 Signaling Pathways, the Mechanism of Artesunate on Inflammation in Osteoporosis in Ovariectomized Rats was …
G Wang, J Tan, C Huang, Y Xu, Z Yang… - Frontiers in Bioscience …, 2024 - imrpress.com
5 天前 - … to bone metabolism. Additionally, we established a postmenopausal osteoporosis
rat model to investigate the in vivo effects of ART on bone tissue pathology, bone density, …
rat model to investigate the in vivo effects of ART on bone tissue pathology, bone density, …
Regorafenib Attenuates Osteoclasts Differentiation by Inhibiting the NF-κB, NFAT, ERK, and p38 Signaling Pathways
L Zhou, P Su, X Luo, X Zhong, Q Liu, Y Su, C Zeng… - ACS …, 2024 - ACS Publications
6 天前 - … Osteolytic diseases such as osteoporosis and neoplastic bone metastases are
caused … to have potential curative effects in animal models of pulmonary emphysema, (53) …
caused … to have potential curative effects in animal models of pulmonary emphysema, (53) …
Preventing bisphosphonate induced osteonecrosis of the jaw with a polyguanidine conjugate (GuaDex): A promising new approach
A Cantorán-Castillo, B Beltrán-Salinas… - Bone, 2024 - Elsevier
6 天前 - … , Paget's disease, bone metastases from breast/prostate cancer, and multiple …
rat model using metformin treatment as prevention (metformin is a bi-guanidine), the treatment …
rat model using metformin treatment as prevention (metformin is a bi-guanidine), the treatment …
OPEN ACCESS EDITED BY
S Brogi, HM Mora-Montes, H Xin… - … and development of …, 2024 - books.google.com
13 天前 - … Although several candidate vaccines have been identified, and they appear to be
efficient and safe in animal models, only two candidates have reached clinical trials Phase I in …
efficient and safe in animal models, only two candidates have reached clinical trials Phase I in …
[HTML][HTML] Transient receptor potential vanilloid 1 interacts with Toll-like receptor 4 (TLR4)/cluster of differentiation 14 (CD14) signaling pathway in lipopolysaccharide …
JCN Hsu, HW Tseng, CH Chen, TS Lee - Experimental Animals, 2024 - ncbi.nlm.nih.gov
21 天前 - … Our results showed that treatment with LPS increased the association of TRPV1
with TLR4 and CD14 in WT BMDMs (Figs. 5A and B). Moreover, genetic disruption of the …
with TLR4 and CD14 in WT BMDMs (Figs. 5A and B). Moreover, genetic disruption of the …
Investigating the effect of a small molecule, Inhibitor of Nuclear Import (INI-43) as a pan-cancer treatment
S Rahman - 2024 - open.uct.ac.za
22 天前 - … -mediated nuclear import and showed anti-cancer effects against cervical and
oesophageal cancer cells using both cell culture and animal models. In this study, we expanded …
oesophageal cancer cells using both cell culture and animal models. In this study, we expanded …
Effectiveness of desertliving cistanche in managing hyperlipidemic osteoporosis in ovariectomized rats through the PI3K/AKT signaling pathway
JY Lin, HM Kuang, K Rong, L Peng, JJ Kuang… - Journal of Orthopaedic …, 2024 - Springer
24 天前 - … Therefore, this study established a PMOP rat model to assess this aspect further. …
and treatment group were fed a high-fat diet for 4 weeks to induce the hyperlipidemic rat model…
and treatment group were fed a high-fat diet for 4 weeks to induce the hyperlipidemic rat model…