A rat model of polymicrobial infection in full-thickness excision wounds

V Gupta, A Tyagi - Journal of Tissue Viability, 2021 - Elsevier
Aim A reproducible animal model is required to study the pathophysiology of wound
infections and for development of effective therapeutic interventions. The objective of this
study was to produce an infected skin wound model utilizing the cecal microbiota in non-
immunocompromised rats. Materials and methods An excision wound was created on the
dorsal surface of rats and inoculated with different concentration of cecal slurry (CS). Wound
progression was investigated macroscopically by wound scoring and imaging. The rats were …
以上显示的是最相近的搜索结果。 查看全部搜索结果