A review of neuroimaging findings of apathy in Alzheimer's disease
International psychogeriatrics, 2014•cambridge.org
Background: Apathy is one of the most frequent “behavioral and psychological signs and
symptoms of dementia”(BPSD) encountered in Alzheimer's disease (AD). There is a growing
interest in the early diagnosis of apathetic elderly patients in the community since apathy
has been associated with reduced daily functioning, caregiver distress, and poor outcome.
The generalization of neuroimaging techniques might be able to offer help in this domain.
Methods: Within this context we conducted an extensive electronic search from the …
symptoms of dementia”(BPSD) encountered in Alzheimer's disease (AD). There is a growing
interest in the early diagnosis of apathetic elderly patients in the community since apathy
has been associated with reduced daily functioning, caregiver distress, and poor outcome.
The generalization of neuroimaging techniques might be able to offer help in this domain.
Methods: Within this context we conducted an extensive electronic search from the …
Background
Apathy is one of the most frequent “behavioral and psychological signs and symptoms of dementia” (BPSD) encountered in Alzheimer's disease (AD). There is a growing interest in the early diagnosis of apathetic elderly patients in the community since apathy has been associated with reduced daily functioning, caregiver distress, and poor outcome. The generalization of neuroimaging techniques might be able to offer help in this domain.
Methods
Within this context we conducted an extensive electronic search from the databases included in the National Library of Medicine as well as PsychInfo and Google Scholar for neuroimaging findings of apathy in AD.
Results
Neuroimaging findings lend support to the notion that frontal-subcortical networks are involved in the occurrence of apathy in AD.
Conclusions
Longitudinal studies comparing patients and normal individuals might allow us to infer on the association between apathy and neurodegenerative diseases and what can brain imaging markers tell us about the characterization of this association, thus revealing disease patterns, helping to distinguish clinically distinct cognitive syndromes, and allowing predictions.
Cambridge University Press以上显示的是最相近的搜索结果。 查看全部搜索结果