[HTML][HTML] A study of the effect of Zataria multiflora extract on methicillin resistant staphylococcus aureus
Jundishapur Journal of Microbiology, 2013•brieflands.com
Background: One of the most common nasocomial bacteria is methicillin resistant
Staphylococcus aureus (MRSA). Today, herbal extracts like Zataria multiflora from the
Lamiaceae family are increasingly used. Objectives: In this study, the antibacterial effect of Z.
multiflora on 75 strains of was evaluated. Materials and Methods: The strains of
Staphylococcus aureus were examined for isolation of strains. 75 out of 232 strains were
diagnosed as by oxacillin 6µg/mL screening method. The extracts of Z. multiflora were …
Staphylococcus aureus (MRSA). Today, herbal extracts like Zataria multiflora from the
Lamiaceae family are increasingly used. Objectives: In this study, the antibacterial effect of Z.
multiflora on 75 strains of was evaluated. Materials and Methods: The strains of
Staphylococcus aureus were examined for isolation of strains. 75 out of 232 strains were
diagnosed as by oxacillin 6µg/mL screening method. The extracts of Z. multiflora were …
Background
One of the most common nasocomial bacteria is methicillin resistant Staphylococcus aureus (MRSA). Today, herbal extracts like Zataria multiflora from the Lamiaceae family are increasingly used.
Objectives
In this study, the antibacterial effect of Z. multiflora on 75 strains of was evaluated.
Materials and Methods
The strains of Staphylococcus aureus were examined for isolation of strains. 75 out of 232 strains were diagnosed as by oxacillin 6µg /mL screening method. The extracts of Z. multiflora were prepared from dried leaves using a maceration method. The antibacterial activity of the extract with initial concentration of 200 µg /mL was determined by the micro broth dilution method.
Results
The obtained results showed that the minimum inhibitory concentration (MIC) varied from 2 to 16µg /mL for strains. It inhibited the growth of S. epidermidis, S. saprophyticus and methicillin sensitive S. aureus (MSSA) by about 8-16 µg/mL. The minimum bactericidal concentration (MBC) of the extract that could destroy 62.2% strains and the other examined bacteria was 512 µg /mL or more.
Conclusions
In conclusion, it seems that Z. multiflora extracts could inhibit the growth of all of the mentioned bacteria. We noticed that the bactericidal effect of Z. multiflora extracts was less than its bacteriostatic effects.
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