A well‐tolerated core needle muscle biopsy process suitable for children and adults

F Barthelemy, JD Woods, S Nieves‐Rodriguez… - Muscle & …, 2020 - Wiley Online Library
Serial muscle biopsies within clinical trials for Duchenne muscular dystrophy (DMD) are
critical to document therapeutic responses. Less invasive means of sampling muscle are
needed. We analyzed a retrospective consecutive case‐series cohort of vacuum‐assisted
core needle muscle biopsy procedures performed on healthy and dystrophic individuals at a
single institution assessing for safety and reliability of obtaining sufficient high‐quality biopsy
tissue for histologic assessment in adult and pediatric subjects. Of 471 muscle cores from …

[PDF][PDF] A well tolerated core needle muscle biopsy process suitable for children and adults

SF Nelson - researchgate.net
Methods We analyzed a retrospective consecutive case-series cohort of vacuum-assisted
core needle muscle biopsy procedures performed on healthy and dystrophic individuals at a
single institution assessing for safety and reliability of obtaining sufficient high quality biopsy
tissue for histologic assessment in adult and pediatric subjects.
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